RWDD3

RWDD3

Identifiers

RWDD3, RSUME, RWD domain containing 3

External IDs

OMIM: 615875; MGI: 1920420; GeneCards: RWDD3

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2EBK, 4Y1L

Gene location (Human)

Chr.	Chromosome 1 (human)

Band	1p21.3	Start	95,234,210 bp
Band	1p21.3	End	95,247,225 bp

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)

Band	3\|3 G1	Start	120,949,047 bp
Band	3\|3 G1	End	120,965,344 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

endometrium

body of pancreas

Achilles tendon

right lobe of liver

nucleus accumbens

amygdala

putamen

olfactory zone of nasal mucosa

caudate nucleus

corpus callosum

Top expressed in

medial ganglionic eminence

lumbar subsegment of spinal cord

supraoptic nucleus

arcuate nucleus

ventromedial nucleus

dentate gyrus

paraventricular nucleus of hypothalamus

dorsomedial hypothalamic nucleus

median eminence

embryo

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	cytoplasm nucleus
Biological process	negative regulation of NF-kappaB transcription factor activity positive regulation of protein sumoylation positive regulation of hypoxia-inducible factor-1alpha signaling pathway
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


25950


66568


ENSG00000122481


ENSMUSG00000028133


Q9Y3V2


Q8VIL2

RefSeq (mRNA)


NM_001128142 NM_001199682 NM_001278247 NM_001278248 NM_015485


NM_025637 NM_028456

RefSeq (protein)


NP_001121614 NP_001186611 NP_001265176 NP_001265177 NP_056300


n/a

Location (UCSC)

Chr 1: 95.23 – 95.25 Mb

Chr 3: 120.95 – 120.97 Mb

PubMed search

View/Edit Human

View/Edit Mouse

RWD domain-containing protein 3 is a protein that in humans is encoded by the RWDD3 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000122481 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028133 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
↑ "Entrez Gene: RWDD3 RWD domain containing 3".

Further reading

Carbia-Nagashima A, Gerez J, Perez-Castro C, et al. (2008). "RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia". Cell. 131 (2): 309–23. doi:10.1016/j.cell.2007.07.044. hdl:20.500.12110/paper_00928674_v131_n2_p309_CarbiaNagashima. PMID 17956732. S2CID 12486303.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.

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