SCMH1

SCMH1
Identifiers
Aliases	SCMH1, Scml3, sex comb on midleg homolog 1 (Drosophila), Scm polycomb group protein homolog 1
External IDs	OMIM: 616396; MGI: 1352762; GeneCards: SCMH1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2P0K
Gene location (Human)
Chr.	Chromosome 1 (human)
End	41,242,154 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	120,387,383 bp
RNA expression pattern
	Top expressed in
	muscle layer of sigmoid colon; ; popliteal artery; ; tibial arteries; ; body of uterus; ; gastric mucosa; ; thoracic aorta; ; ascending aorta; ; Descending thoracic aorta; ; right coronary artery; ; left uterine tube;
	Top expressed in
	saccule; ; Rostral migratory stream; ; tail of embryo; ; ectoderm; ; otic vesicle; ; neural layer of retina; ; zygote; ; otic placode; ; genital tubercle; ; secondary oocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	chromocenter; nucleoplasm; nucleus;
Biological process	multicellular organism development; chromatin remodeling; regulation of transcription, DNA-templated; transcription, DNA-templated; spermatogenesis; anterior/posterior pattern specification; negative regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	22955
	29871
	ENSG00000010803
	ENSMUSG00000000085
	Q96GD3
	Q8K214
NM_001031694; NM_001172218; NM_001172219; NM_001172220; NM_001172221;
	NM_001172222; NM_012236; NM_001350667; NM_001350668; NM_001394299; NM_001394300; NM_001394301; NM_001394302; NM_001394303; NM_001394304; NM_001394305; NM_001394306; NM_001394307; NM_001394308; NM_001394309; NM_001394311
NM_001159630; NM_013883; NM_001355423; NM_001355424; NM_001379184;
	NM_001379185; NM_001379186
NP_001026864; NP_001165689; NP_001165690; NP_001165691; NP_001165692;
	NP_001165693; NP_036368; NP_001337596; NP_001337597
NP_001153102; NP_038911; NP_001342352; NP_001342353; NP_001366113;
	NP_001366114; NP_001366115; NP_001391019; NP_001391031; NP_001391032
	Wikidata
View/Edit Human	View/Edit Mouse

Polycomb protein SCMH1 is a protein that in humans is encoded by the SCMH1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000010803 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000085 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Berger J, Kurahashi H, Takihara Y, Shimada K, Brock HW, Randazzo F (September 1999). "The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34". Gene. 237 (1): 185–91. doi:10.1016/S0378-1119(99)00285-1. PMID 10524249.
↑ "Entrez Gene: SCMH1 sex comb on midleg homolog 1 (Drosophila)".

Tomotsune D, Takihara Y, Berger J, Duhl D, Joo S, Kyba M, Shirai M, Ohta H, Matsuda Y, Honda BM, Simon J, Shimada K, Brock HW, Randazzo F (December 1999). "A novel member of murine Polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro". Differentiation; Research in Biological Diversity. 65 (4): 229–39. doi:10.1046/j.1432-0436.1999.6540229.x. PMID 10653359.
Levine SS, Weiss A, Erdjument-Bromage H, Shao Z, Tempst P, Kingston RE (September 2002). "The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans". Molecular and Cellular Biology. 22 (17): 6070–8. doi:10.1128/MCB.22.17.6070-6078.2002. PMC 134016. PMID 12167701.
Luo L, Yang X, Takihara Y, Knoetgen H, Kessel M (February 2004). "The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions". Nature. 427 (6976): 749–53. Bibcode:2004Natur.427..749L. doi:10.1038/nature02305. hdl:11858/00-001M-0000-0012-EE32-1. PMID 14973489. S2CID 8020382.
Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (September 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY (May 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000010803 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000085 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10524249-5] Berger J, Kurahashi H, Takihara Y, Shimada K, Brock HW, Randazzo F (September 1999). "The human homolog of Sex comb on midleg (SCMH1) maps to chromosome 1p34". Gene. 237 (1): 185–91. doi:10.1016/S0378-1119(99)00285-1. PMID 10524249.

[entrez-6] "Entrez Gene: SCMH1 sex comb on midleg homolog 1 (Drosophila)".

SCMH1

References

Further reading