SCPEP1

SCPEP1

Identifiers

SCPEP1, HSCP1, RISC, serine carboxypeptidase 1

External IDs

MGI: 1921867; GeneCards: SCPEP1

Gene location (Human)

Chr.	Chromosome 17 (human)

Band	17q22	Start	56,978,129 bp
Band	17q22	End	57,006,768 bp

Gene location (Mouse)

Chr.	Chromosome 11 (mouse)

Band	11\|11 C	Start	88,814,846 bp
Band	11\|11 C	End	88,846,291 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

right adrenal cortex

monocyte

left adrenal cortex

olfactory zone of nasal mucosa

left lobe of thyroid gland

right lobe of thyroid gland

Descending thoracic aorta

gallbladder

ascending aorta

right coronary artery

Top expressed in

decidua

Gonadal ridge

gastrula

calvaria

pineal gland

external carotid artery

efferent ductule

internal carotid artery

iris

skin of abdomen

More reference expression data


More reference expression data

Gene ontology
Molecular function	carboxypeptidase activity peptidase activity hydrolase activity serine-type carboxypeptidase activity
Cellular component	extracellular region cytosol extracellular exosome
Biological process	proteolysis involved in cellular protein catabolic process retinoic acid metabolic process negative regulation of blood pressure proteolysis
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


59342


74617


ENSG00000121064


ENSMUSG00000000278


Q9HB40


Q920A5

RefSeq (mRNA)


NM_021626


NM_029023

RefSeq (protein)


NP_067639


NP_083299

Location (UCSC)

Chr 17: 56.98 – 57.01 Mb

Chr 11: 88.81 – 88.85 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Retinoid-inducible serine carboxypeptidase is an enzyme that in humans is encoded by the SCPEP1 gene.

See also

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000121064 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000278 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Chen J, Streb JW, Maltby KM, Kitchen CM, Miano JM (September 2001). "Cloning of a novel retinoid-inducible serine carboxypeptidase from vascular smooth muscle cells". The Journal of Biological Chemistry. 276 (36): 34175–34181. doi:10.1074/jbc.M104162200. PMID 11447226.
↑ Clark HF, Gurney AL, Abaya E, Baker K, Baldwin D, Brush J, et al. (October 2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Research. 13 (10): 2265–2270. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
↑ "Entrez Gene: SCPEP1 serine carboxypeptidase 1".

Further reading

Robb GB, Rana TM (May 2007). "RNA helicase A interacts with RISC in human cells and functions in RISC loading". Molecular Cell. 26 (4): 523–537. doi:10.1016/j.molcel.2007.04.016. PMID 17531811.
Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10): 2819–2824. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
Zhang H, Li XJ, Martin DB, Aebersold R (June 2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nature Biotechnology. 21 (6): 660–666. doi:10.1038/nbt827. PMID 12754519. S2CID 581283.

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