SCRN1

SCRN1

Identifiers

SCRN1, SES1, secernin 1

External IDs

OMIM: 614965; MGI: 1917188; GeneCards: SCRN1

Gene location (Human)

Chr.	Chromosome 7 (human)

Band	7p14.3	Start	29,920,104 bp
Band	7p14.3	End	29,990,289 bp

Gene location (Mouse)

Chr.	Chromosome 6 (mouse)

Band	6\|6 B3	Start	54,478,158 bp
Band	6\|6 B3	End	54,543,474 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

trigeminal ganglion

cerebellar vermis

ventricular zone

pons

pars reticulata

superior vestibular nucleus

olfactory bulb

pars compacta

paraflocculus of cerebellum

spinal ganglia

Top expressed in

otolith organ

utricle

habenula

superior cervical ganglion

paraventricular nucleus of hypothalamus

dorsal striatum

arcuate nucleus

median eminence

dorsomedial hypothalamic nucleus

ventral tegmental area

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding dipeptidase activity molecular function
Cellular component	cytoplasm nuclear membrane nucleus
Biological process	proteolysis exocytosis
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


9805


69938


ENSG00000136193


ENSMUSG00000019124


Q12765


Q9CZC8

RefSeq (mRNA)


NM_001145513 NM_001145514 NM_001145515 NM_014766


NM_027268

RefSeq (protein)


NP_001138985 NP_001138986 NP_001138987 NP_055581


NP_081544

Location (UCSC)

Chr 7: 29.92 – 29.99 Mb

Chr 6: 54.48 – 54.54 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Secernin-1 is a protein that in humans is encoded by the SCRN1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000136193 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000019124 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Way G, Morrice N, Smythe C, O'Sullivan AJ (September 2002). "Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells". Molecular Biology of the Cell. 13 (9): 3344–3354. doi:10.1091/mbc.E01-10-0094. PMC 124164. PMID 12221138.
↑ "Entrez Gene: SCRN1 secernin 1".

Further reading

Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Research. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
Nagase T, Seki N, Ishikawa K, Tanaka A, Nomura N (February 1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.
Sanger Centre T, Washington University Genome Sequencing Cente T (November 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–1108. doi:10.1101/gr.8.11.1097. PMID 9847074.
Hoja MR, Wahlestedt C, Höög C (2000). "A visual intracellular classification strategy for uncharacterized human proteins". Experimental Cell Research. 259 (1): 239–246. doi:10.1006/excr.2000.4948. PMID 10942595.
O'Neill EE, Brock CJ, von Kriegsheim AF, Pearce AC, Dwek RA, Watson SP, et al. (March 2002). "Towards complete analysis of the platelet proteome". Proteomics. 2 (3): 288–305. doi:10.1002/1615-9861(200203)2:3<288::AID-PROT288>3.0.CO;2-0. PMID 11921445. S2CID 20643741.
Suda T, Tsunoda T, Uchida N, Watanabe T, Hasegawa S, Satoh S, et al. (May 2006). "Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray". Cancer Science. 97 (5): 411–419. doi:10.1111/j.1349-7006.2006.00194.x. PMC 11159625. PMID 16630140. S2CID 25739515.

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