SERP1

SERP1

Identifiers

SERP1, RAMP4, stress-associated endoplasmic reticulum protein 1, stress associated endoplasmic reticulum protein 1

External IDs

OMIM: 617674; MGI: 92638; GeneCards: SERP1

Gene location (Human)

Chr.	Chromosome 3 (human)

Band	3q25.1	Start	150,541,998 bp
Band	3q25.1	End	150,603,228 bp

Gene location (Mouse)

Chr.	Chromosome 3 (mouse)

Band	3 D\|3 28.58 cM	Start	58,427,238 bp
Band	3 D\|3 28.58 cM	End	58,433,313 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

parotid gland

corpus epididymis

body of pancreas

caput epididymis

bronchial epithelial cell

amniotic fluid

palpebral conjunctiva

mucosa of paranasal sinus

superficial temporal artery

lower lobe of lung

Top expressed in

parotid gland

seminal vesicula

lacrimal gland

submandibular gland

crypt of lieberkuhn of small intestine

olfactory epithelium

lymph node

mesenteric lymph nodes

calvaria

pyloric antrum

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	integral component of membrane cytosol ribosome endoplasmic reticulum membrane membrane endoplasmic reticulum cytoplasmic microtubule
Biological process	skeletal system development muscle organ morphogenesis positive regulation of organ growth post-embryonic development positive regulation of translation IRE1-mediated unfolded protein response positive regulation of growth hormone secretion glucose metabolic process multicellular organism aging protein transport plasma membrane organization positive regulation of insulin secretion endoplasmic reticulum unfolded protein response protein glycosylation
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


27230


28146


ENSG00000120742


ENSMUSG00000027808


Q9Y6X1


Q9Z1W5

RefSeq (mRNA)


NM_014445


NM_030685

RefSeq (protein)


NP_055260


NP_109610

Location (UCSC)

Chr 3: 150.54 – 150.6 Mb

Chr 3: 58.43 – 58.43 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Stress-associated endoplasmic reticulum protein 1 is a protein that in humans is encoded by the SERP1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000120742 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027808 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yamaguchi A, Hori O, Stern DM, Hartmann E, Ogawa S, Tohyama M (Jan 2000). "Stress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylation". J Cell Biol. 147 (6): 1195–204. doi:10.1083/jcb.147.6.1195. PMC 2168098. PMID 10601334.
↑ Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Bocher M, Blocker H, Bauersachs S, Blum H, Lauber J, Dusterhoft A, Beyer A, Kohrer K, Strack N, Mewes HW, Ottenwalder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (Mar 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
↑ "Entrez Gene: SERP1 stress-associated endoplasmic reticulum protein 1".

Further reading

Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

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