SESTD1

SESTD1
Identifiers
Aliases	SESTD1, SOLO, SEC14 and spectrin domain containing 1
External IDs	MGI: 1916262; GeneCards: SESTD1
Gene location (Human)
Chr.	Chromosome 2 (human)
End	179,264,832 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	77,110,936 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus callosum; ; lateral nuclear group of thalamus; ; gastric mucosa; ; inferior ganglion of vagus nerve; ; subthalamic nucleus; ; cartilage tissue; ; secondary oocyte; ; nasal epithelium; ; gonad;
	Top expressed in
	otolith organ; ; utricle; ; trigeminal ganglion; ; hand; ; medial dorsal nucleus; ; Paneth cell; ; lobe of cerebellum; ; lateral geniculate nucleus; ; medial geniculate nucleus; ; spinal ganglia;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphatidic acid binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; 1-phosphatidylinositol binding; protein binding; phosphatidylserine binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylcholine binding; phosphatidylinositol-3,4-bisphosphate binding;
Cellular component	calcium channel complex; intermediate filament cytoskeleton;
Biological process	negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	91404
	228071
	ENSG00000187231
	ENSMUSG00000042272
	Q86VW0
	Q80UK0
	NM_178123
	NM_175465
	NP_835224
	NP_780674
	Wikidata
View/Edit Human	View/Edit Mouse

SEC14 and spectrin domains 1, also known as SEC14 domain and spectrin repeat-containing protein 1 and Solo, is a protein that in humans is encoded by the SESTD1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000187231 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042272 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: SEC14 and spectrin domains 1".

Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Sato T, Mishina M (2003). "Representational difference analysis, high-resolution physical mapping, and transcript identification of the zebrafish genomic region for a motor behavior". Genomics. 82 (2): 218–29. doi:10.1016/S0888-7543(03)00071-5. PMID 12837271.
Rose JE, Behm FM, Drgon T, et al. (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Miehe S, Bieberstein A, Arnould I, et al. (2010). "The phospholipid-binding protein SESTD1 is a novel regulator of the transient receptor potential channels TRPC4 and TRPC5". J. Biol. Chem. 285 (16): 12426–34. doi:10.1074/jbc.M109.068304. PMC 2852980. PMID 20164195.
Trynka G, Zhernakova A, Romanos J, et al. (2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling". Gut. 58 (8): 1078–83. doi:10.1136/gut.2008.169052. PMID 19240061. S2CID 17111427.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000187231 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042272 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SEC14 and spectrin domains 1".

SESTD1

References

Further reading