SF3B5

SF3B5

Identifiers

SF3B5, SF3b10, Ysf3, splicing factor 3b subunit 5

External IDs

OMIM: 617847; MGI: 1913375; GeneCards: SF3B5

Gene location (Human)

Chr.	Chromosome 6 (human)

Band	6q24.2	Start	144,094,884 bp
Band	6q24.2	End	144,095,573 bp

Gene location (Mouse)

Chr.	Chromosome 10 (mouse)

Band	10\|10 A2	Start	12,881,087 bp
Band	10\|10 A2	End	12,884,927 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

anterior pituitary

mucosa of transverse colon

granulocyte

right adrenal gland

left adrenal cortex

right adrenal cortex

olfactory zone of nasal mucosa

body of pancreas

skin of leg

skin of abdomen

Top expressed in

internal carotid artery

endocardial cushion

efferent ductule

abdominal wall

mandibular prominence

external carotid artery

maxillary prominence

renal corpuscle

endothelial cell of lymphatic vessel

migratory enteric neural crest cell

More reference expression data


More reference expression data

Gene ontology
Molecular function	RNA binding
Cellular component	U12-type spliceosomal complex spliceosomal complex precatalytic spliceosome nucleus U2 snRNP nucleoplasm U2-type precatalytic spliceosome
Biological process	mRNA processing RNA splicing mRNA splicing, via spliceosome
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


83443


66125


ENSG00000169976


ENSMUSG00000078348


Q9BWJ5


Q923D4

RefSeq (mRNA)


NM_031287


NM_175102

RefSeq (protein)


NP_112577


NP_780311

Location (UCSC)

Chr 6: 144.09 – 144.1 Mb

Chr 10: 12.88 – 12.88 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Splicing factor 3B subunit 5 is a protein that in humans is encoded by the SF3B5 gene.

The protein is a part of splicing factor 3b.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000169976 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000078348 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Will CL, Urlaub H, Achsel T, Gentzel M, Wilm M, Luhrmann R (Sep 2002). "Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein". EMBO J. 21 (18): 4978–88. doi:10.1093/emboj/cdf480. PMC 126279. PMID 12234937.
↑ "Entrez Gene: SF3B5 splicing factor 3b, subunit 5, 10kDa".

Further reading

Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

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