SFXN3

SFXN3
Identifiers
Aliases	SFXN3, BA108L7.2, SFX3, sideroflexin 3, SLC56A3
External IDs	OMIM: 615571; MGI: 2137679; GeneCards: SFXN3
Gene location (Human) Chr. Chromosome 10 (human) Band 10q24.31 Start 101,031,234 bp End 101,041,244 bp
Gene location (Mouse) Chr. Chromosome 19 (mouse) Band 19|19 C3 Start 45,035,942 bp End 45,044,822 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cerebellar hemisphere tendon of biceps brachii right hemisphere of cerebellum paraflocculus of cerebellum saphenous vein pancreatic ductal cell ascending aorta Descending thoracic aorta cerebellar vermis synovial joint Top expressed in aortic valve ascending aorta visual cortex superior frontal gyrus primary visual cortex cumulus cell external carotid artery substantia nigra saccule piriform cortex More reference expression data BioGPS n/a
Gene ontology Molecular function ion transmembrane transporter activity serine transmembrane transporter activity Cellular component integral component of membrane mitochondrial membranes mitochondrion membrane Biological process ion transmembrane transport iron ion homeostasis ion transport transmembrane transport one-carbon metabolic process serine import into mitochondrion mitochondrial transmembrane transport amino acid transport Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 81855 94280 Ensembl ENSG00000107819 ENSMUSG00000025212 UniProt Q9BWM7 Q91V61 RefSeq (mRNA) NM_030971 NM_001178012 NM_001178013 NM_053197 NM_001362379 NM_001362380 NM_001362381 RefSeq (protein) NP_112233 NP_001171483 NP_001171484 NP_444427 NP_001349308 NP_001349309 NP_001349310 Location (UCSC) Chr 10: 101.03 – 101.04 Mb Chr 19: 45.04 – 45.04 Mb PubMed search
Wikidata
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Sideroflexin-3 is a protein that in humans is encoded by the SFXN3 gene. Sideroflexin-3 is a membrane transporter that belongs to solute carrier family 56. It is associated with amino acid transport and mitochondrial transmembrane transport, and also has role in the one-carbon metabolic process.

References