SLA2

Src-like-adapter 2 is a protein that in humans is encoded by the SLA2 gene.

Function

This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.

Interactions

SLA2 has been shown to interact with Cbl gene.

References

Further reading


Uses material from the Wikipedia article SLA2, released under the CC BY-SA 4.0 license.