SURF2

SURF2
Identifiers
Aliases	SURF2, SURF-2, surfeit 2
External IDs	OMIM: 185630; MGI: 98444; GeneCards: SURF2
Gene location (Human)
Chr.	Chromosome 9 (human)
End	133,361,158 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	26,810,195 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; gonad; ; olfactory zone of nasal mucosa; ; temporal lobe; ; amygdala; ; prefrontal cortex; ; anterior cingulate cortex; ; dorsolateral prefrontal cortex; ; substantia nigra;
	Top expressed in
	Ileal epithelium; ; morula; ; morula; ; otic placode; ; embryo; ; tail of embryo; ; otic vesicle; ; embryo; ; saccule; ; epiblast;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function;
Cellular component	plasma membrane; nucleolus; nucleus; nuclear speck; cellular component;
Biological process	biological process;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	6835
	20931
	ENSG00000281024; ENSG00000148291
	ENSMUSG00000014873
	Q15527
	P09926
	NM_017503; NM_001278928
	NM_013678
	NP_001265857; NP_059973
	NP_038706
	Wikidata
View/Edit Human	View/Edit Mouse

SURF2 is a protein which in humans is encoded by the SURF2 gene. SURF2 is a member of the surfeit gene family. The SURF2 molecule interacts with beta-1, 4-Gal-T3, uPAR, and WDR20. As part of the surfeit gene cluster, SURF2 is one of several tightly linked genes that do not share sequence similarity. SURF2 maps to human chromosome 9q34.2 and shares a bidirectional promoter with SURF1 on the opposite strand. A bidirectional promoter activity is expected in the intergenic region between SURF1 and SURF2, as seen in mice.

References

1 2 3 ENSG00000148291 GRCh38: Ensembl release 89: ENSG00000281024, ENSG00000148291 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000014873 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lennard A, Gaston K, Fried M (November 1994). "The Surf-1 and Surf-2 genes and their essential bidirectional promoter elements are conserved between mouse and human". DNA Cell Biol. 13 (11): 1117–26. doi:10.1089/dna.1994.13.1117. PMID 7702754.
↑ Duhig T, Ruhrberg C, Mor O, Fried M (August 1998). "The human Surfeit locus". Genomics. 52 (1): 72–8. doi:10.1006/geno.1998.5372. PMID 9740673.
↑ "SURF2 Protein Human Recombinant | Surfeit 2 Antigen | ProSpec".

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 ENSG00000148291 GRCh38: Ensembl release 89: ENSG00000281024, ENSG00000148291 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000014873 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7702754-5] Lennard A, Gaston K, Fried M (November 1994). "The Surf-1 and Surf-2 genes and their essential bidirectional promoter elements are conserved between mouse and human". DNA Cell Biol. 13 (11): 1117–26. doi:10.1089/dna.1994.13.1117. PMID 7702754.

[pmid9740673-6] Duhig T, Ruhrberg C, Mor O, Fried M (August 1998). "The human Surfeit locus". Genomics. 52 (1): 72–8. doi:10.1006/geno.1998.5372. PMID 9740673.

[7] "SURF2 Protein Human Recombinant | Surfeit 2 Antigen | ProSpec".