SYPL1

SYPL1
Identifiers
Aliases	SYPL1, H-SP1, SYPL, synaptophysin like 1
External IDs	OMIM: 616665; MGI: 108081; GeneCards: SYPL1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	106,112,576 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	33,029,859 bp
RNA expression pattern
	Top expressed in
	epithelium of nasopharynx; ; C1 segment; ; germinal epithelium; ; mucosa of paranasal sinus; ; olfactory zone of nasal mucosa; ; parotid gland; ; gingival epithelium; ; minor salivary glands; ; mucosa of pharynx; ; oral cavity;
	Top expressed in
	spermatid; ; conjunctival fornix; ; corneal stroma; ; ascending aorta; ; parotid gland; ; crypt of lieberkuhn of small intestine; ; aortic valve; ; seminal vesicula; ; transitional epithelium of urinary bladder; ; triceps brachii muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transporter activity; syntaxin-1 binding;
Cellular component	synaptic vesicle; secretory granule; cytoplasmic vesicle membrane; membrane; melanosome; cytoplasmic vesicle; integral component of synaptic vesicle membrane; integral component of membrane; integral component of plasma membrane; extracellular exosome; synaptic vesicle membrane;
Biological process	chemical synaptic transmission; transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	6856
	19027
	ENSG00000008282
	ENSMUSG00000020570
	Q16563
	O09117
	NM_006754; NM_182715
	NM_013635; NM_198710
NP_006745; NP_874384; NP_001368839; NP_001368840; NP_001368841;
	NP_001368842; NP_001368844; NP_001368845; NP_001368846; NP_001368847; NP_001368848; NP_001368849; NP_001368850
	NP_038663; NP_942003
	Wikidata
View/Edit Human	View/Edit Mouse

Synaptophysin-like protein 1 is a protein that in humans is encoded by the SYPL1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000008282 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020570 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: SYPL1 synaptophysin-like 1".

Zhong CZ, Hayzer DJ, Runge MS (1992). "Molecular cloning of a cDNA encoding a novel protein related to the neuronal vesicle protein synaptophysin". Biochimica et Biophysica Acta. 1129 (2): 235–238. doi:10.1016/0167-4781(92)90495-l. PMID 1730063.
Leube RE (May 1994). "Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human". Differentiation; Research in Biological Diversity. 56 (3): 163–171. doi:10.1046/j.1432-0436.1994.5630163.x. PMID 8034131.
Haass NK, Kartenbeck MA, Leube RE (1996). "Pantophysin is a ubiquitously expressed synaptophysin homologue and defines constitutive transport vesicles". The Journal of Cell Biology. 134 (3): 731–746. doi:10.1083/jcb.134.3.731. PMC 2120938. PMID 8707851.
Sanger Centre T, Washington University Genome Sequencing Cente T (November 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–1108. doi:10.1101/gr.8.11.1097. PMID 9847074.
Windoffer R, Borchert-Stuhlträger M, Haass NK, Thomas S, Hergt M, Bulitta CJ, et al. (June 1999). "Tissue expression of the vesicle protein pantophysin". Cell and Tissue Research. 296 (3): 499–510. doi:10.1007/s004410051310. PMID 10370136. S2CID 6765747.
Brooks CC, Scherer PE, Cleveland K, Whittemore JL, Lodish HF, Cheatham B (January 2000). "Pantophysin is a phosphoprotein component of adipocyte transport vesicles and associates with GLUT4-containing vesicles". The Journal of Biological Chemistry. 275 (3): 2029–2036. doi:10.1074/jbc.275.3.2029. PMID 10636906.
Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, et al. (November 2006). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes". Journal of Proteome Research. 5 (11): 3135–3144. doi:10.1021/pr060363j. PMID 17081065.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000008282 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000020570 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SYPL1 synaptophysin-like 1".

SYPL1

References

Further reading