Saglin

Saglin is a protein produced by the salivary glands of mosquitoes. It is thought that this protein allows the malarial sporozoite to bind to the salivary glands, allowing invasion. It is currently under investigation as a potential drug target to help control transmission of the disease by controlling transmission in the vector.

References

  1. ↑ Okulate et al. 2007 Identification and molecular characterization of a novel protein Saglin as a target of monoclonal antibodies affecting salivary gland infectivity of Plasmodium sporozoites
  2. ↑ The Saglin Project http://bioquest.org/oakwood2008/2008/08/this-is-the-saglin-project/