Schisandrin

Schisandrins (schizandrins) are a group of bioactive chemical compounds found in Schisandra rubriflora, Schisandra sphenanthera, and Schisandra chinensis. Schizandrin is a lignan.

Schisandrin
Schisandrin. IUPAC Name: 3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaen-9-ol

IUPAC Name*

3,4,5,14,15,16-hexamethoxy-9,10-dimethyltricyclo[10.4.0.02,7]hexadeca-1(16),2,4,6,12,14-hexaen-9-ol *Computed by Lexichem TK 2.7.0 (PubChem release 2021.05.07)

CAS Common Chemistry

7432-28-2

Molecular Formula

Molecular Weight

432.5

PubChem CID

23915

Characteristics

Schisandra chinensis (S. chinensis) berries were originally a component of traditional herbal medicine in China, Korea, and other east Asian countries.[citation needed]

Examples include:

Chemical structures of schisandrins A-C

References

  1. ↑ "WikiData".
  2. ↑ Park, SY; Park, SJ; Park, TG; Rajasekar, S; Lee, SJ; Choi, YW (2013). "Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microglia". International Immunopharmacology. 17 (2): 415–26. doi:10.1016/j.intimp.2013.06.032. PMID 23859871.
  3. ↑ "LOTUS - the natural products occurrence database".
  4. ↑ Ehambarampillai, D.; Wan, M. L. (2025). "A comprehensive review of Schisandra chinensis lignans: pharmacokinetics, pharmacological mechanisms, and future prospects in disease prevention and treatment". Chinese Medicine. 20 (1): 47. doi:10.1186/s13020-025-01096-z. PMC 11984061. PMID 40205412.
  5. ↑ "PubChem \ United States National Library of Medicine".
  6. ↑ "CAS Common Chemistry".
  7. ↑ "EPA DSSTox". Archived from the original on March 27, 2023.
  8. ↑ "European Chemicals Agency (ECHA)".
  9. ↑ "PubChem CID \ United States National Library of Medicine".