Simplicius

Simplicius may refer to:

Pope Simplicius (d. 483 AD)
Simplicius of Cilicia (d. c. 560 AD), philosopher
Saint Simplicius, legendary 'founding' bishop of the Sardinian Diocese of Civita
Simplicius, Constantius and Victorinus (fl. 2nd century), Roman martyrs and saints
Simplicius, Faustinus and Beatrix (d. 302 or 303 AD), Roman martyrs and saints

Simplicius Simplicissimus, a picaresque novel about the character of the same name
Simplicius (operetta), an operetta by Johann Strauss II
A character in Dialogue Concerning the Two Chief World Systems, a 1632 work by Galileo