TBRG1

TBRG1

Identifiers

TBRG1, NIAM, TB-5, transforming growth factor beta regulator 1

External IDs

OMIM: 610614; MGI: 1100877; GeneCards: TBRG1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2WZO

Gene location (Human)

Chr.	Chromosome 11 (human)

Band	11q24.2	Start	124,622,836 bp
Band	11q24.2	End	124,635,926 bp

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)

Band	9\|9 A4	Start	37,560,059 bp
Band	9\|9 A4	End	37,568,608 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

granulocyte

gastric mucosa

rectum

monocyte

right lung

appendix

body of pancreas

spleen

tibia

prefrontal cortex

Top expressed in

dermis

endocardial cushion

Gonadal ridge

decidua

seminal vesicula

yolk sac

tooth

molar

migratory enteric neural crest cell

skin of external ear

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	nucleus
Biological process	DNA replication cell cycle protein stabilization negative regulation of cell population proliferation protein localization to nucleoplasm
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


84897


21376


ENSG00000154144


ENSMUSG00000011114


Q3YBR2


Q3UB74

RefSeq (mRNA)


NM_032811


NM_025289

RefSeq (protein)


NP_116200


NP_079565

Location (UCSC)

Chr 11: 124.62 – 124.64 Mb

Chr 9: 37.56 – 37.57 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Transforming growth factor beta regulator 1 is a protein that in humans is encoded by the TBRG1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000154144 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000011114 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Babalola GO, Schultz RM (Oct 1995). "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta". Mol Reprod Dev. 41 (2): 133–9. doi:10.1002/mrd.1080410203. PMID 7654366. S2CID 84997218.
↑ Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE (Jan 2007). "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability". J Biol Chem. 282 (2): 1322–33. doi:10.1074/jbc.M609612200. PMID 17110379.
↑ "Entrez Gene: TBRG1 transforming growth factor beta regulator 1".

Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Tompkins V, Hagen J, Zediak VP, Quelle DE (2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi:10.4161/cc.5.6.2560. PMID 16582619.

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