TP53I11

TP53I11

Identifiers

TP53I11, PIG11, tumor protein p53 inducible protein 11

External IDs

OMIM: 617867; MGI: 2670995; GeneCards: TP53I11

Gene location (Human)

Chr.	Chromosome 11 (human)

Band	11p11.2	Start	44,885,903 bp
Band	11p11.2	End	44,951,306 bp

Gene location (Mouse)

Chr.	Chromosome 2 (mouse)

Band	2\|2 E1	Start	93,017,893 bp
Band	2\|2 E1	End	93,032,104 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

right hemisphere of cerebellum

right auricle of heart

right uterine tube

left uterine tube

ganglionic eminence

apex of heart

mucosa of transverse colon

popliteal artery

tibial arteries

upper lobe of left lung

Top expressed in

superior cervical ganglion

genital tubercle

tail of embryo

thymus

ventricular zone

habenula

transitional epithelium of urinary bladder

interventricular septum

suprachiasmatic nucleus

dentate gyrus of hippocampal formation granule cell

More reference expression data


More reference expression data

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


9537


277414


ENSG00000175274


ENSMUSG00000068735


O14683


Q4QQM4

RefSeq (mRNA)

NM_001076787 NM_001258320 NM_001258321 NM_001258322 NM_001258323
NM_001258324 NM_006034 NM_001318384 NM_001318385 NM_001318386 NM_001318387 NM_001318388 NM_001318389 NM_001318390


NM_001025246 NM_001356535 NM_001356536 NM_001356537

RefSeq (protein)

NP_001245249 NP_001245250 NP_001245251 NP_001245252 NP_001245253
NP_001305313 NP_001305314 NP_001305315 NP_001305316 NP_001305317 NP_001305318 NP_001305319 NP_006025


NP_001020417 NP_001343464 NP_001343465 NP_001343466

Location (UCSC)

Chr 11: 44.89 – 44.95 Mb

Chr 2: 93.02 – 93.03 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Tumor protein p53-inducible protein 11 is a protein that in humans is encoded by the TP53I11 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000175274 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000068735 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B (Sep 1997). "A model for p53-induced apoptosis". Nature. 389 (6648): 300–5. Bibcode:1997Natur.389..300P. doi:10.1038/38525. PMID 9305847. S2CID 4429638.
↑ "Entrez Gene: TP53I11 tumor protein p53 inducible protein 11".

Further reading

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Liang XQ, Cao EH, Zhang Y, Qin JF (2004). "P53-induced gene 11 (PIG11) involved in arsenic trioxide-induced apoptosis in human gastric cancer MGC-803 cells". Oncol. Rep. 10 (5): 1265–9. doi:10.3892/or.10.5.1265. PMID 12883691.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Liang XQ, Cao EH, Zhang Y, Qin JF (2004). "A P53 target gene, PIG11, contributes to chemosensitivity of cells to arsenic trioxide". FEBS Lett. 569 (1–3): 94–8. Bibcode:2004FEBSL.569...94L. doi:10.1016/j.febslet.2004.05.057. PMID 15225615. S2CID 25975446.
Fingrut O, Reischer D, Rotem R, et al. (2006). "Jasmonates induce nonapoptotic death in high-resistance mutant p53-expressing B-lymphoma cells". Br. J. Pharmacol. 146 (6): 800–8. doi:10.1038/sj.bjp.0706394. PMC 1751213. PMID 16170329.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Xiong XF, Li H, Cao EH (2007). "PIG11 protein binds to DNA in sequence-independent manner in vitro". Biochem. Biophys. Res. Commun. 358 (1): 29–34. doi:10.1016/j.bbrc.2007.04.048. PMID 17482569.

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