TRAPPC4

TRAPPC4

Identifiers

TRAPPC4, HSPC172, PTD009, SBDN, SYNBINDIN, TRS23, CGI-104, trafficking protein particle complex 4, NEDESBA, trafficking protein particle complex subunit 4

External IDs

OMIM: 610971; MGI: 1926211; GeneCards: TRAPPC4

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2J3T, 2JSN, 2ZMV

Gene location (Human)

Chr.	Chromosome 11 (human)

Band	11q23.3	Start	119,018,763 bp
Band	11q23.3	End	119,025,454 bp

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)

Band	9\|9 A5.2	Start	44,314,995 bp
Band	9\|9 A5.2	End	44,318,897 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

islet of Langerhans

anterior pituitary

right testis

left testis

stromal cell of endometrium

ganglionic eminence

right adrenal gland

left adrenal gland

left adrenal cortex

human kidney

Top expressed in

medial ganglionic eminence

right kidney

ventricular zone

neural tube

morula

otic placode

granulocyte

facial motor nucleus

dentate gyrus of hippocampal formation granule cell

embryo

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	cytosol Golgi apparatus synaptic vesicle synapse dendrite endoplasmic reticulum Golgi stack Golgi membrane TRAPP complex
Biological process	dendrite development COPII vesicle coating vesicle-mediated transport endoplasmic reticulum to Golgi vesicle-mediated transport
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


51399


60409


ENSG00000280495 ENSG00000196655


ENSMUSG00000032112


Q9Y296


Q9ES56

RefSeq (mRNA)

NM_016146 NM_001318486 NM_001318488 NM_001318489 NM_001318490
NM_001318492 NM_001318494


NM_021789

RefSeq (protein)

NP_001305415 NP_001305417 NP_001305418 NP_001305419 NP_001305421
NP_001305423 NP_057230


NP_068561

Location (UCSC)

Chr 11: 119.02 – 119.03 Mb

Chr 9: 44.31 – 44.32 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Trafficking protein particle complex subunit 4 is a protein that in humans is encoded by the TRAPPC4 gene. It is part of TRAPP complex.

References

1 2 3 ENSG00000196655 GRCh38: Ensembl release 89: ENSG00000280495, ENSG00000196655 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032112 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
↑ "Entrez Gene: TRAPPC4 trafficking protein particle complex 4".
↑ "TRAPPC4 trafficking protein particle complex subunit 4 [Homo sapiens (human)] - Gene - NCBI". www.ncbi.nlm.nih.gov. Retrieved 2025-06-02.

Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gavin AC, Bösche M, Krause R, et al. (2002). "Functional organization of the yeast proteome by systematic analysis of protein complexes". Nature. 415 (6868): 141–7. Bibcode:2002Natur.415..141G. doi:10.1038/415141a. PMID 11805826. S2CID 4425555.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells". Genome Res. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
Ethell IM, Hagihara K, Miura Y, et al. (2000). "Synbindin, a Novel Syndecan-2–Binding Protein in Neuronal Dendritic Spines". J. Cell Biol. 151 (1): 53–68. doi:10.1083/jcb.151.1.53. PMC 2189810. PMID 11018053.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

v t e PDB gallery
2j3t: THE CRYSTAL STRUCTURE OF THE BET3-TRS33-BET5-TRS23 COMPLEX.

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