TRIM52

TRIM52
Identifiers
Aliases	TRIM52, RNF102, tripartite motif containing 52
External IDs	MGI: 3045276; GeneCards: TRIM52
Enzyme activity
Gene location (Human)
Chr.	Chromosome 5 (human)
End	181,261,150 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	106,373,293 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; right uterine tube; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; granulocyte; ; pituitary gland; ; anterior pituitary; ; left ovary;
	Top expressed in
	testicle; ; spermatid; ; spermatocyte; ; embryo; ; primary oocyte; ; secondary oocyte; ; zygote; ; blastocyst; ; liver; ; spleen;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; metal ion binding;
Cellular component	intracellular anatomical structure; nuclear body;
Biological process	positive regulation of NF-kappaB transcription factor activity;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	84851
	212085
	ENSG00000183718
	ENSMUSG00000022113
	Q96A61
	Q8CDV4
	NM_032765; NM_001346048; NM_001346049; NM_001346050; NM_001346051
	NM_198601
NP_001332977; NP_001332978; NP_001332979; NP_001332980; NP_116154;
	NP_116154.1
	NP_941003
	Wikidata
View/Edit Human	View/Edit Mouse

TRIM52, also known as RNF102, is a protein in the tripartite motif family. In humans, it is encoded by the gene of the same name. Knockdown of this gene induces apoptosis. This gene's overexpression has been implicated in multiple types of cancer including ovarian cancer, gastric cancer, and colon cancer.

References

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