Macoilin

MACO1
Identifiers
Aliases	MACO1, MACOILIN, transmembrane protein 57, macoilin 1, TMEM57
External IDs	OMIM: 610301; MGI: 1913396; GeneCards: MACO1
Gene location (Human)
Chr.	Chromosome 1 (human)
End	25,500,209 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	134,580,656 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; ganglionic eminence; ; buccal mucosa cell; ; Skeletal muscle tissue of biceps brachii; ; body of pancreas; ; gastrocnemius muscle; ; islet of Langerhans; ; muscle of thigh; ; Achilles tendon; ; liver;
	Top expressed in
	superior cervical ganglion; ; Rostral migratory stream; ; hand; ; Gonadal ridge; ; spermatocyte; ; zygote; ; ganglionic eminence; ; otolith organ; ; lacrimal gland; ; utricle;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function; microtubule binding; actin filament binding;
Cellular component	integral component of membrane; neuron projection; axon; cell projection; synapse; nuclear membrane; neuron projection terminus; membrane; nucleus; endoplasmic reticulum; rough endoplasmic reticulum membrane;
Biological process	brain development; neuronal signal transduction; chemotaxis;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	55219
	66146
	ENSG00000204178
	ENSMUSG00000028826
	Q8N5G2
	Q7TQE6
	NM_001282564; NM_018202
	NM_025382; NM_001355499; NM_001355500; NM_001355501
	NP_001269493; NP_060672
	NP_079658; NP_001342428; NP_001342429; NP_001342430
	Wikidata
View/Edit Human	View/Edit Mouse

Macoilin is a protein that in humans is encoded by the MACO1 gene (previously TMEM57). This protein is involved in regulating neuronal activity.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000204178 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028826 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Transmembrane protein 57". Retrieved 2017-10-09.
↑ "Macoilin". UniProt consortium. Retrieved 2026-10-03.

Aulchenko YS, Ripatti S, Lindqvist I, Boomsma D, Heid IM, Pramstaller PP, Penninx BW, Janssens AC, Wilson JF, Spector T, Martin NG, Pedersen NL, Kyvik KO, Kaprio J, Hofman A, Freimer NB, Jarvelin MR, Gyllensten U, Campbell H, Rudan I, Johansson A, Marroni F, Hayward C, Vitart V, Jonasson I, Pattaro C, Wright A, Hastie N, Pichler I, Hicks AA, Falchi M, Willemsen G, Hottenga JJ, de Geus EJ, Montgomery GW, Whitfield J, Magnusson P, Saharinen J, Perola M, Silander K, Isaacs A, Sijbrands EJ, Uitterlinden AG, Witteman JC, Oostra BA, Elliott P, Ruokonen A, Sabatti C, Gieger C, Meitinger T, Kronenberg F, Döring A, Wichmann HE, Smit JH, McCarthy MI, van Duijn CM, Peltonen L (2009). "Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts". Nat. Genet. 41 (1): 47–55. doi:10.1038/ng.269. PMC 2687074. PMID 19060911.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD (2009). "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip". Am. J. Hum. Genet. 85 (5): 628–42. doi:10.1016/j.ajhg.2009.10.014. PMC 2775832. PMID 19913121.

This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000204178 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000028826 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Transmembrane protein 57". Retrieved 2017-10-09.

[uniprot-6] "Macoilin". UniProt consortium. Retrieved 2026-10-03.

Macoilin

See also

References

Further reading