UBL5

UBL5
Identifiers
Aliases	UBL5, HUB1, ubiquitin like 5
External IDs	OMIM: 606849; MGI: 1913427; GeneCards: UBL5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1P0R, 4PYU
Gene location (Human)
Chr.	Chromosome 19 (human)
End	9,830,115 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	20,647,140 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right testis; ; left testis; ; right adrenal gland; ; mucosa of transverse colon; ; left adrenal cortex; ; right adrenal cortex; ; C1 segment; ; anterior cingulate cortex; ; monocyte;
	Top expressed in
	choroid plexus of fourth ventricle; ; interventricular septum; ; corneal stroma; ; ventricular zone; ; cardiac muscle tissue of left ventricle; ; yolk sac; ; lip; ; granulocyte; ; zygote; ; plantaris muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein tag;
Cellular component	cytoplasm; nucleus;
Biological process	mRNA splicing, via spliceosome; positive regulation of protein targeting to mitochondrion;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	59286
	66177
	ENSG00000198258
	ENSMUSG00000084786
	Q9BZL1
	Q9EPV8
	NM_024292; NM_001048241
	NM_025401; NM_001310746
	NP_001041706; NP_077268; NP_001041706.1; NP_077268.1
	NP_001297675; NP_079677; NP_001347954; NP_001347955; NP_001347956
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene.

It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans.

Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).[supplied by OMIM]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000198258 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000084786 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 "Entrez Gene: UBL5 ubiquitin-like 5".
↑ Mitochondrial Stress Signals Revise an Old Aging Theory - DOI 10.1016/j.cell.2010.12.023

External links

Overview of all the structural information available in the PDB for UniProt: Q9BZL1 (Human Ubiquitin-like protein 5) at the PDBe-KB.
Overview of all the structural information available in the PDB for UniProt: Q9EPV8 (Mouse Ubiquitin-like protein 5) at the PDBe-KB.

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000198258 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000084786 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 "Entrez Gene: UBL5 ubiquitin-like 5".

[6] Mitochondrial Stress Signals Revise an Old Aging Theory - DOI 10.1016/j.cell.2010.12.023

UBL5

References

Further reading

External links