UBP1

UBP1

Identifiers

UBP1, LBP-1B, LBP-1a, LBP1A, LBP1B, upstream binding protein 1 (LBP-1a), upstream binding protein 1

External IDs

OMIM: 609784; MGI: 104889; GeneCards: UBP1

Gene location (Human)

Chr.	Chromosome 3 (human)

Band	3p22.3	Start	33,388,336 bp
Band	3p22.3	End	33,441,371 bp

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)

Band	9\|9 F3	Start	113,760,002 bp
Band	9\|9 F3	End	113,806,270 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

tibia

rectum

sural nerve

visceral pleura

popliteal artery

tibial arteries

appendix

right coronary artery

smooth muscle tissue

endothelial cell

Top expressed in

Paneth cell

medullary collecting duct

secondary oocyte

tibiofemoral joint

primary oocyte

zygote

ureter

renal corpuscle

saccule

otic vesicle

More reference expression data


More reference expression data

Gene ontology
Molecular function	DNA binding transcription corepressor activity sequence-specific DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component	nucleus nucleoplasm cytosol
Biological process	viral genome replication negative regulation of transcription, DNA-templated regulation of transcription, DNA-templated angiogenesis transcription, DNA-templated regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


7342


22221


ENSG00000153560


ENSMUSG00000009741


Q9NZI7


Q811S7

RefSeq (mRNA)


NM_001128160 NM_001128161 NM_014517

NM_001083319 NM_013699 NM_001372507 NM_001372508 NM_001372510
NM_001372511 NM_001372512 NM_001372514

RefSeq (protein)


NP_001121632 NP_001121633 NP_055332

NP_001076788 NP_038727 NP_001359436 NP_001359437 NP_001359439
NP_001359440 NP_001359441 NP_001359443

Location (UCSC)

Chr 3: 33.39 – 33.44 Mb

Chr 9: 113.76 – 113.81 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Upstream-binding protein 1 is a protein that in humans is encoded by the UBP1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000153560 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000009741 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yoon JB, Li G, Roeder RG (Mar 1994). "Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro". Mol Cell Biol. 14 (3): 1776–85. doi:10.1128/mcb.14.3.1776. PMC 358535. PMID 8114710.
↑ "Entrez Gene: UBP1 upstream binding protein 1 (LBP-1a)".

Further reading

Kato H, Horikoshi M, Roeder RG (1991). "Repression of HIV-1 transcription by a cellular protein". Science. 251 (5000): 1476–9. Bibcode:1991Sci...251.1476K. doi:10.1126/science.2006421. PMID 2006421.
Parada CA, Yoon JB, Roeder RG (1995). "A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro". J. Biol. Chem. 270 (5): 2274–83. doi:10.1074/jbc.270.5.2274. PMID 7836461.
Huang N, Miller WL (2000). "Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc". J. Biol. Chem. 275 (4): 2852–8. doi:10.1074/jbc.275.4.2852. PMID 10644752.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Zhao H, Li J, Jiang L (2004). "Inhibition of HIV-1 TAR RNA-Tat peptide complexation using poly(acrylic acid)". Biochem. Biophys. Res. Commun. 320 (1): 95–9. doi:10.1016/j.bbrc.2004.05.148. PMID 15207707.
Huang N, Miller WL (2005). "LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells". Mol. Endocrinol. 19 (2): 409–20. doi:10.1210/me.2004-0086. PMID 15471945.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

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