USP19

USP19
Identifiers
Aliases	USP19, ZMYND9, ubiquitin specific peptidase 19
External IDs	OMIM: 614471; MGI: 1918722; GeneCards: USP19
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WH0, 4X3G
Enzyme activity
Gene location (Human)
Chr.	Chromosome 3 (human)
End	49,120,938 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	108,379,536 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; muscle of thigh; ; right uterine tube; ; right lobe of thyroid gland; ; right adrenal cortex; ; granulocyte; ; apex of heart; ; body of tongue; ; right hemisphere of cerebellum; ; left adrenal gland;
	Top expressed in
	secondary oocyte; ; primary oocyte; ; zygote; ; neural layer of retina; ; muscle of thigh; ; choroid plexus of fourth ventricle; ; superior frontal gyrus; ; granulocyte; ; lip; ; ventricular zone;
	More reference expression data
	n/a
Gene ontology
Molecular function	Hsp90 protein binding; cysteine-type peptidase activity; metal ion binding; Lys48-specific deubiquitinase activity; peptidase activity; protein binding; thiol-dependent deubiquitinase; hydrolase activity; ubiquitin protein ligase binding;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytosol; nucleus;
Biological process	protein K48-linked deubiquitination; regulation of protein stability; ubiquitin-dependent protein catabolic process; protein stabilization; response to endoplasmic reticulum stress; proteolysis; regulation of ERAD pathway; regulation of cellular response to hypoxia; negative regulation of skeletal muscle tissue development; positive regulation of cell cycle process; ubiquitin-dependent ERAD pathway; negative regulation of proteasomal protein catabolic process; protein deubiquitination;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	10869
	71472
	ENSG00000172046
	ENSMUSG00000006676
	O94966
	Q3UJD6
NM_001199160; NM_001199161; NM_001199162; NM_006677; NM_001351098;
	NM_001351099; NM_001351100; NM_001351101; NM_001351102; NM_001351103; NM_001351104; NM_001351105; NM_001351106; NM_001351107; NM_001351108; NM_001389594; NM_001389595; NM_001389596; NM_001389597; NM_001389598; NM_001389599; NM_001389600; NM_001389601; NM_001389602; NM_001389603; NM_001389604; NM_001389605; NM_001389606; NM_001389607; NM_001389608; NM_001400288; NM_001400290; NM_001400292; NM_001400293; NM_001400294; NM_001400295; NM_001400296; NM_001400297; NM_001400298; NM_001400299
	NM_001168371; NM_001168372; NM_001168373; NM_027804; NM_145407
NP_001186089; NP_001186090; NP_001186091; NP_006668; NP_001338027;
	NP_001338028; NP_001338029; NP_001338030; NP_001338031; NP_001338032; NP_001338033; NP_001338034; NP_001338035; NP_001338036; NP_001338037
	NP_001161843; NP_001161844; NP_001161845; NP_082080; NP_663382
	Wikidata
View/Edit Human	View/Edit Mouse

Ubiquitin specific peptidase 19 is a protein that in humans is encoded by the USP19 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172046 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000006676 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Ubiquitin specific peptidase 19". Retrieved 2016-02-18.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Ubiquitin carboxyl-terminal hydrolase 19 (USP19)

USP19

References

External links

Further reading