USS Persistent is a name used more than once by the United States Navy:
- USS Persistent (PYc-48), a coastal patrol yacht commissioned 16 October 1940.
- USS Persistent (MSO-491), a fleet minesweeper commissioned 3 February 1956.
- USNS Persistent (T-AGOS-6), a Stalwart-class ocean surveillance ship that operated during the 1980s.
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.