USS Weiss has been the name of more than one United States Navy ship, and may refer to:
- USS Weiss (DE-378), a destroyer escort cancelled during construction in 1944
- USS Weiss (DE-719), a destroyer escort converted during construction into a fast transport
- USS Weiss (APD-135), formerly Weiss (DE-719), a fast transport in commission from 1945 to 1970
This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.