| Upía River | |
|---|---|
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| Location | |
| Country | Colombia |
| Physical characteristics | |
| Source | |
| • location | Lake Tota |
| Mouth | |
• location | Meta River |

Upía River, a river in Colombia originating at Lake Tota (5°29'31" N, 72°56'04" W), is a tributary of the Meta River flowing into the Orinoco River basin.