Long periods of immobility that can be encountered from driving, flying, bed rest/hospitalization, or having an orthopedic cast. Recommendations by clinicians to reduce venous stasis and DVT/PE often encourage increasing walking, calf exercises, and intermittent pneumatic compression when possible.
Weakened Venous valves: these are crucial towards ensuring upward flow to the heart from the lower extremities. If weakened, they may fail to close properly which leads to backwards blood flow/blood pooling. This can lead to slower blood flow in the veins.
↑Barbara G. Wells; Joseph T. DiPiro; Terry L. Schwinghammer; Gary R. Matzke; Gary C. Yee; Robert L. Talbert; L. Michael Posey (2008). Pharmacotherapy Handbook. McGraw-Hill Professional. p.163. ISBN9780071485012.