ViroCap

ViroCap is a test announced in 2015 by researchers at Washington University in St. Louis which can detect most of the infectious viruses which affect both humans and animals. It was demonstrated to be as sensitive as the various Polymerase chain reaction assays for the viruses. The test examines two million sequences of genetic data from viruses. The research was published in September 2015 in the online journal Genome Research.

The researchers followed up their work in 2018, publishing comparisons between Metagenomic Shotgun Sequencing (MSS) and ViroCap.

ViroCap has since been utilised in a study conducted by the University Medical Center Utrecht, Utrecht, Netherlands in 2019.

References

  1. ↑ Feller, Stephen "New test detects all the viruses that infect people, animals," UPI, 29 September 2015. Retrieved 29 September, 2015
  2. ↑ "Newsroom- Washington University in St. Louis,"New test detects all viruses that infect people, animals," 29 September 2015. Retrieved 29 September 2015
  3. ↑ Wylie, Todd N., Wylie, Kristine M., Herter, Brandi N. and Storch, Gregory A. "Enhanced virome sequencing through solution-based capture enrichment" Genome Research, 22 September 2015. DOI 10.1101/gr.191049.115
  4. ↑ Wylie, Kristine M.; Wylie, Todd N.; Buller, Richard; Herter, Brandi; Cannella, Maria T.; Storch, Gregory A. (December 2018). "Detection of Viruses in Clinical Samples by Use of Metagenomic Sequencing and Targeted Sequence Capture". Journal of Clinical Microbiology. 56 (12): e01123–18. doi:10.1128/JCM.01123-18. ISSN 1098-660X. PMC 6258860. PMID 30232133.
  5. ↑ Jansen, Suze A.; Nijhuis, Wouter; Leavis, Helen L.; Riezebos-Brilman, Annelies; Lindemans, Caroline A.; Schuurman, Rob (March 2020). "Targeted Sequence Capture Metagenomics (ViroCap) to Detect Viruses in Stool Samples of Hematopoietic Stem Cell Transplantation Patients". Biology of Blood and Marrow Transplantation. 26 (3): S174–S175. doi:10.1016/j.bbmt.2019.12.731. ISSN 1083-8791. Archived from the original on 2024-06-02.