ZDHHC3

ZDHHC3

Identifiers

ZDHHC3, DHHC-3, GODZ, ZNF373, zinc finger DHHC-type containing 3, DHHC3, zinc finger DHHC-type palmitoyltransferase 3

External IDs

OMIM: 617150; MGI: 1926134; GeneCards: ZDHHC3

Enzyme activity
EC #	BRENDA	ExPASy	KEGG	MetaCyc
2.3.1.225	↗	↗	↗	↗

Gene location (Human)

Chr.	Chromosome 3 (human)

Band	3p21.31	Start	44,915,257 bp
Band	3p21.31	End	44,976,185 bp

Gene location (Mouse)

Chr.	Chromosome 9 (mouse)

Band	9\|9 F4	Start	123,066,160 bp
Band	9\|9 F4	End	123,113,205 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

left testis

right testis

rectum

stromal cell of endometrium

skin of leg

left adrenal gland

right adrenal gland

sperm

skin of abdomen

left adrenal cortex

Top expressed in

granulocyte

muscle of thigh

lip

tail of embryo

genital tubercle

pontine nuclei

left lung

epiblast

dorsal tegmental nucleus

yolk sac

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein-cysteine S-palmitoyltransferase activity palmitoyltransferase activity transferase activity acyltransferase activity
Cellular component	integral component of membrane Golgi membrane Golgi apparatus membrane endoplasmic reticulum
Biological process	protein targeting protein palmitoylation protein targeting to membrane peptidyl-L-cysteine S-palmitoylation localization within membrane protein localization to photoreceptor outer segment
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


51304


69035


ENSG00000163812


ENSMUSG00000025786


Q9NYG2


Q8R173

RefSeq (mRNA)

NM_001135179 NM_001135180 NM_016598 NM_001330761 NM_001349376
NM_001349377 NM_001349378 NM_001349379 NM_001349380 NM_001349381


NM_026917

RefSeq (protein)

NP_001128651 NP_001317690 NP_057682 NP_001336305 NP_001336306
NP_001336307 NP_001336308 NP_001336309 NP_001336310

NP_081193 NP_001359467 NP_001359468 NP_001359469 NP_001359470
NP_001359471 NP_001359472 NP_001359473 NP_001359475 NP_001359476 NP_001359477 NP_001359478 NP_001359479 NP_001359480 NP_001359481 NP_001359482

Location (UCSC)

Chr 3: 44.92 – 44.98 Mb

Chr 9: 123.07 – 123.11 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Palmitoyltransferase ZDHHC3 is an enzyme that in humans is encoded by the ZDHHC3 gene that contains a DHHC domain.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000163812 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025786 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: ZDHHC3 zinc finger, DHHC-type containing 3".

Further reading

Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Uemura T, Mori H, Mishina M (2002). "Isolation and characterization of Golgi apparatus-specific GODZ with the DHHC zinc finger domain". Biochem. Biophys. Res. Commun. 296 (2): 492–6. doi:10.1016/S0006-291X(02)00900-2. PMID 12163046.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.

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