 Isidro Lángara (1952–54) Juan Ricardo Faccio (1977–78) Manuel Lapuente (1978–84)- Hugo Fernández (1985–87)
 Pedro García Barros (1988–89)- Manuel Lapuente (1988–93)
- Ignacio Trelles (1990–91)
 Jorge Vieira (1990–92)- Muricy Ramalho (1993)
- Alfredo Tena (1993–95)
- Hugo Fernández (1995–96)
- Aníbal Ruiz (1996–97)
- Julio González (1997–98)
- Alfredo Tena (Jan 1, 1999 – April 5, 1999)
- José Mari Bakero (July 1, 1999 – Sept 27, 1999)
- Miguel Mejía Barón (2000)
- Mario Carrillo (Sept 16, 2000 – Dec 31, 2001)
- Tomás Boy (Jan 1, 2002 – March 25, 2002)
- Alejandro Domínguez (interim) (April 6, 2002 – April 12, 2002)
- Tomás Boy (interim) (April 25, 2002 – June 30, 2002)
- Ignacio Ambríz (July 1, 2002 – June 30, 2003)
- Víctor Vucetich (Sept 16, 2002 – March 3, 2003)
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- Hugo Fernández (2003)
- Mario Carrillo (July 1, 2003 – Dec 31, 2003)
 Roberto Saporiti (March 18, 2005 – June 30, 2005)- Jorge Aravena (July 1, 2005 – Dec 31, 2005)
- César Luis Menotti (2006)
- José Luis Sánchez (July 1, 2006 – Sept 16, 2008)
- Mario Carrillo (Sept 17, 2008 – Dec 31, 2008)
- José Luis Sánchez (Jan 1, 2009 – Aug 23, 2010)
- Eduardo Fentanes (Aug 24, 2010 – Sept 13, 2010)
- José Luis Trejo (Sept 14, 2010 – Feb 15, 2011)
- Héctor Hugo Eugui (Feb 15, 2011 – June 30, 2011)
- Sergio Bueno (July 1, 2011 – Dec 31, 2011)
 Juan Carlos Osorio (Jan 1, 2012 – March 21, 2012)- Daniel Bartolotta (March 21, 2012 – Aug 18, 2012)
- Daniel Guzman (Aug 20, 2012 – Oct 30, 2012)
- Carlos Poblete (Oct 30, 2012 – Dec 31, 2012)
- Manuel Lapuente (Jan 1, 2013 – Aug 14, 2013)
- Rubén Omar Romano (Aug 14, 2013 – Aug 24, 2014)
- José Luis Sánchez (Aug 25, 2014–14)
- José Guadalupe Cruz (Dec 8, 2014 – May 18, 2015)
- Pablo Marini (May 30, 2015–April 18, 2016)
- Ricardo Valiño (April 19, 2016–January 30, 2017)
 José Cardozo (January 30, 2017–)
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