Frontotemporal dementia

Frontotemporal dementia (FTD), or frontotemporal degeneration disease or frontotemporal neurocognitive disorder, includes some types of dementia.


FTD is the clinical presentation of frontotemporal lobar degeneration. It is characterized by progressive neuronal loss predominantly involving the frontal or temporal lobes, and typical loss of over 70% of spindle neurons, while other neuron types remain intact.

Second only to Alzheimer's disease (AD) in prevalence, FTD accounts for 20% of young-onset dementia cases.

Common signs and symptoms include significant changes in social and personal behavior, apathy, blunting of emotions, and deficits in both expressive and receptive language.

Types: One type of FTD, is "semantic-variant primary progressive aphasia, ... that (mostly or) primarily (does something to, or) affects the areas in the brain responsible for speech and language", according to media; Furthermore, one [can have] trouble [remembering] faces and names.

References

  1. ↑ Olney NT, Spina S, Miller BL (May 2017). "Frontotemporal dementia". Neurologic Clinics. 35 (2): 339–374. doi:10.1016/j.ncl.2017.01.008. PMC 5472209. PMID 28410663.
  2. ↑ Diagnostic and statistical manual of mental disorders: DSM-5 (5th ed.). Arlington, Virginia: American Psychiatric Association. 2013. pp. 614–618. ISBN 978-0-89042-554-1.
  3. ↑ "ICD-11 – Mortality and Morbidity Statistics". icd.who.int. World Health Organization.{{cite web}}: CS1 maint: deprecated archival service (link)
  4. ↑ "Brain Cells for Socializing". Smithsonian. Retrieved 30 October 2015.
  5. ↑ Snowden JS, Neary D, Mann DM; Neary; Mann (February 2002). "Frontotemporal dementia". Br J Psychiatry. 180 (2): 140–3. doi:10.1192/bjp.180.2.140. PMID 11823324. S2CID 231797268.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ↑ https://stanfordmag.org/contents/my-brothers-keeper. Retrieved 2025-08-15