The Loddon River, is the second longest rive in Victoria, Australia. It is 392 km (244 mi) in length and has 19 smaller rivers and creeks as tributaries. The river's source is in the Great Dividing Range, west of the town of Trentham. It flows north into the Little Murray River near Swan Hill. It drops 567 m (1,860 ft) over its length. It is part of the Murray–Darling basin.
The river flows through the towns of Newstead, Bridgewater, Serpentine, Boort and Kerang.
There are two major reservoirs along the river, Cairn Curran and Laanecoorie.