11C ME@HAPTHI

11C ME@HAPTHI
Identifiers
	IUPAC name (S)-1-(3-Hydroxy-4-([11C]methylamino)butyl)-3-phenyl-1,3-dihydrobenzo[c][1,2,5]thiadiazole,2,2-dioxide;
CAS Number	1033218-58-4 ;
PubChem CID	165360096;
ChemSpider	129562584;
CompTox Dashboard (EPA)	DTXSID601335993 ;
Chemical and physical data
Formula	C17H21N3O3S
Molar mass	347.43 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [11CH3]NC[C@@H](O)CCN1C2=C(C=CC=C2)N(C2=CC=CC=C2)S1(=O)=O;
	InChI InChI=1S/C17H21N3O3S/c1-18-13-15(21)11-12-19-16-9-5-6-10-17(16)20(24(19,22)23)14-7-3-2-4-8-14/h2-10,15,18,21H,11-13H2,1H3/t15-/m0/s1/i1-1; Key:OIFBYCGNUDQJBL-FZTOSIJBSA-N;

[11C]ME@HAPTHI is a chemical compound used as a radiotracer to image the norepinephrine transporter (NET) protein using positron emission tomography (PET). The NET protein is of research interest for its role in various neuropsychiatric disorders, such as ADHD and depression.

References

1 2 Rami-Mark C, Berroterán-Infante N, Philippe C, Foltin S, Vraka C, Hoepping A, Lanzenberger R, Hacker M, Mitterhauser M, Wadsak W (Dec 2015). "Radiosynthesis and first preclinical evaluation of the novel norepinephrine transporter pet-ligand [(11)C]ME@HAPTHI". EJNMMI Research. 5 (34) 34: 113. doi:10.1186/s13550-015-0113-3. PMC 4467816. PMID 26061602.

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Identifiers

IUPAC name (S)-1-(3-Hydroxy-4-([11C]methylamino)butyl)-3-phenyl-1,3-dihydrobenzo[c][1,2,5]thiadiazole,2,2-dioxide
CAS Number	1033218-58-4^Y
PubChem CID	165360096
ChemSpider	129562584
CompTox Dashboard (EPA)	DTXSID601335993
Chemical and physical data
Formula	C₁₇H₂₁N₃O₃S
Molar mass	347.43 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES [11CH3]NC[C@@H](O)CCN1C2=C(C=CC=C2)N(C2=CC=CC=C2)S1(=O)=O
InChI InChI=1S/C17H21N3O3S/c1-18-13-15(21)11-12-19-16-9-5-6-10-17(16)20(24(19,22)23)14-7-3-2-4-8-14/h2-10,15,18,21H,11-13H2,1H3/t15-/m0/s1/i1-1 Key:OIFBYCGNUDQJBL-FZTOSIJBSA-N