| 1978 Colgate Series Championships | |
|---|---|
| Date | November 14–19 |
| Edition | 2nd |
| Category | Virginia Slims circuit |
| Draw | 8S / 4D |
| Prize money | $250,000 |
| Surface | Hard / outdoor |
| Location | Palm Springs, California, U.S. |
| Venue | Mission Hills Country Club |
| Champions | |
| Singles | |
 Chris Evert | |
| Doubles | |
| Billie Jean King Martina Navratilova | |
The 1978 Colgate Series Championships was a women's tennis tournament played on outdoor hard courts at the Mission Hills Country Club in Palm Springs, California in the United States that was the season-ending tournament of the 1978 Virginia Slims World Championship Series. It was the second edition of the tournament and was held from November 14 through November 19, 1978. Chris Evert won the singles title and earned $75,000 first-prize money.
