The draft started with Penn State teammates Courtney Brown and LaVar Arrington being selected consecutively, making them the only Penn State players to go number one and two in the same draft. The New York Jets had four first-round draft picks, the most by any team in the history of the draft (17 teams have had three picks but no other has had four).
In the explanations below, (D) denotes trades that took place during the 2000 Draft, while (PD) indicates trades completed pre-draft.
Round 1
↑No. 2: New Orleans → Washington (PD). New Orleans traded first- and third-round selections (2nd and 64th overall), and 1999 first-, third-, fourth-, fifth-, sixth- and seventh-round selections to Washington in exchange for a 1999 first-round selection.
↑No. 3: San Francisco → Washington (PD). San Francisco traded a first-round selection (3rd overall) to Washington in exchange for two first-round selections, a fourth-round selection and a fifth-round selection (12th, 24th, 119th and 154th overall).
↑No. 5: Atlanta → Baltimore (PD). Atlanta traded a first-round selection (5th overall) to Baltimore in exchange for a 1999 second-round selection.
↑No. 10: Denver → Baltimore (PD). Denver traded a first-round selection (10th overall) to Baltimore in exchange for first- and second-round selections (15th and 45th overall).
↑No. 12: Carolina → Washington → San Francisco → NY Jets. Multiple trades: San Francisco → NY Jets (PD). San Francisco traded a first-round selection (12th overall) to the NY Jets in exchange for first- and second-round selections (16th and 48th overall). Washington → San Francisco (PD). See Round 1: San Francisco → Washington. Carolina → Washington (PD). Carolina sent a first-round selection (12th overall) and a 1999 first-round selection to Washington as compensation for signing non-exclusive franchise-tagged free agent DT Sean Gilbert.
↑No. 13: San Diego → Tampa Bay → NY Jets. Multiple trades: Tampa Bay → NY Jets (PD). Tampa Bay traded two first-round picks (13th and 27th overall) to the NY Jets in exchange for WR Keyshawn Johnson. San Diego → Tampa Bay (PD). San Diego traded a first-round selection (13th overall) to Tampa Bay in exchange for a 1998 second-round selection.
↑No. 16: New England → NY Jets → San Francisco. Multiple trades: New England → NY Jets (PD). New England traded a first-round selection (16th overall) and 2001 fourth- and seventh-round selections to the NY Jets in exchange for a 2001 fifth-round selection and a 2002 seventh-round selection as compensation for signing head coach Bill Belichick. NY Jets → San Francisco (D). See Round 1: San Francisco → NY Jets.
↑No. 19: Dallas → Seattle (PD). Dallas traded a first-round selection (19th overall) and a 2001 first-round selection to Seattle in exchange for WR Joey Galloway.
↑No. 23: Miami → Carolina (PD). Miami traded a first-round selection (23rd overall) to Carolina in exchange for a 1998 second-round selection.
↑No. 51: Carolina → Tampa Bay (D). Carolina traded a second-round selection (51st overall) to Tampa Bay in exchange for second- and fourth-round selections (57th and 120th overall).
↑No. 56: Washington → Minnesota (PD). Washington traded a second-round selection (56th overall), and 1999 first- and third-round selections to Minnesota in exchange for QB Brad Johnson.
↑No. 61: Tennessee → Philadelphia (D). Tennessee traded a second-round selection (61st overall) to Philadelphia in exchange for third- and fifth-round selections (68th and 135th overall).
↑No. 77: Oakland → Pittsburgh (PD). Oakland traded a third-round selection (77th overall) to Pittsburgh in exchange for two 1999 fifth-round selections (146th and 163rd overall).
↑No. 80: Dallas → Seattle (PD). Dallas traded a third-round selection (80th overall) to Seattle in exchange for WR James McKnight.
↑No. 86: Seattle → San Francisco (D). Seattle traded a third-round selection (86th overall) to San Francisco in exchange for fourth- and fifth-round selections (119th and 154th overall).
↑No. 87: Washington → Chicago (PD). Washington traded a third-round selection (87th overall) and 1999 first-, third-, fourth- and fifth-round selections to Chicago in exchange for a 1999 first-round selection.
Round 4
↑No. 98: San Francisco → Green Bay (D). San Francisco traded a fourth-round selection (98th overall) to Green Bay in exchange for fourth- and fifth-round selections (108th and 132nd overall).
↑No. 104: Chicago → St. Louis (D). Chicago traded a fourth-round selection (104th overall) to St. Louis in exchange for fourth-, fifth- and seventh-round selections (125th, 150th and 225th overall).
↑No. 106: Baltimore → Minnesota (PD). Baltimore traded a fourth-round selection (106th overall) and a 1999 sixth-round selection to Minnesota in exchange for a sixth-round selection (191st overall) and G Everett Lindsay.
↑No. 108: NY Jets → Green Bay → San Francisco. Multiple trades: NY Jets → Green Bay (PD). NY Jets traded a fourth-round selection (108th overall) to Green Bay in exchange for QB Rick Mirer. Green Bay → San Francisco (D). See Round 4: San Francisco → Green Bay.
↑No. 111: Detroit → Philadelphia → San Diego. Multiple trades: Detroit → Philadelphia (PD). Detroit traded a fourth-round selection (111th overall) to Philadelphia in exchange for a 1999 fifth-round selection. Philadelphia → San Diego (D). Philadelphia traded a fourth-round selection (111th overall) to San Diego in exchange for a 2001 third-round selection.
↑No. 112: Carolina → Denver (PD). Carolina traded a fourth-round selection (112th overall) and a 1999 third-round selection to Denver in exchange for QB Jeff Lewis.
↑No. 119: Washington → San Francisco → Seattle. Multiple trades: Washington → San Francisco (D). See Round 1: San Francisco → Washington. San Francisco → Seattle (D). See Round 3: Seattle → San Francisco.
↑No. 132: San Francisco → Green Bay → San Francisco. Multiple trades: San Francisco → Green Bay (PD). San Francisco traded a fifth-round selection (132nd overall) to Green Bay in exchange for CB Craig Newsome. Green Bay → San Francisco (D). See Round 4: San Francisco → Green Bay.
↑No. 138: Chicago → New Orleans → Indianapolis. Multiple trades: Chicago → New Orleans (PD). Chicago traded a fifth-round selection (138th overall) to New Orleans in exchange for WR Eddie Kennison. New Orleans → Indianapolis (D). New Orleans traded a fifth-round selection (138th overall) to Indianapolis in exchange for fifth- and sixth-round selections (158th and 195th overall).
↑No. 139: Denver → St. Louis (PD). Denver traded a fifth-round selection (139th overall) and a 2001 fifth-round selection to St. Louis in exchange for S Billy Jenkins.
↑No. 148: San Diego → Baltimore (PD). San Diego traded a fifth-round selection (148th overall) to Baltimore in exchange for QB Jim Harbaugh.
↑No. 150: Baltimore → Detroit → St. Louis → Chicago → San Francisco. Multiple trades: Baltimore → Detroit (PD). Baltimore traded a fifth-round selection (150th overall) and a 1999 third-round selection to Detroit in exchange for QB Scott Mitchell. Detroit → St. Louis (PD). Detroit traded fifth- and seventh-round selections (150th and 220th) to St. Louis in exchange for RB Greg Hill. St. Louis → Chicago (D). See Round 4: Chicago → St. Louis. Chicago → San Francisco (D). Chicago traded a fifth-round selection (150th overall) to San Francisco in exchange for sixth- and seventh-round selections (170th and 209th overall).
↑No. 151: Seattle → Green Bay (PD). Seattle traded a fifth-round selection (151st overall) and RB Ahman Green to Green Bay in exchange for a sixth-round selection (185th overall) and CB Fred Vinson.
↑No. 154: Washington → San Francisco → Seattle → Denver. Multiple trades: Washington → San Francisco (D). See Round 1: San Francisco → Washington. San Francisco → Seattle (D). See Round 3: Seattle → San Francisco. Seattle → Denver (D). Seattle traded a fifth-round selection (154th overall) to Denver in exchange for sixth- and seventh-round selections (175th and 231st overall).
↑No. 155: Minnesota → Washington (PD). Minnesota sent a fifth-round selection (155th overall) to Washington as compensation for signing restricted free agent OL Brad Badger.
↑No. 161: St. Louis → New England (PD). St. Louis traded a fifth-round selection (161st overall) to New England in exchange for DE Mike Jones.
Round 6
↑No. 167: Cleveland → Miami (PD). Cleveland traded a sixth-round selection (167th overall) and a conditional 2001 fifth-round selection to Miami in exchange for RB Karim Abdul-Jabbar.
↑No. 188: Miami → Kansas City (PD). Miami traded a sixth-round selection (188th overall) and 1999 second- and third-round selections to Kansas City in exchange for a 1999 second-round selection.
↑No. 189: Kansas City → St. Louis → Denver. Multiple trades: Kansas City → St. Louis (PD). Kansas City traded a sixth-round selection (189th overall) to St. Louis in exchange for TE Mitch Jacoby. St. Louis → Denver (D). St. Louis traded a sixth-round selection (189th overall) to Denver in exchange for RB Derek Loville.
↑No. 208: New Orleans → Kansas City (PD). New Orleans traded a seventh-round selection (208th overall) to Kansas City in exchange for a seventh-round selection (228th overall) as compensation for hiring defensive backs coach Ron Zook as defensive coordinator.
↑No. 209: San Francisco → Chicago → Cleveland. Multiple trades: San Francisco → Chicago (D). See Round 5: Chicago → San Francisco. Chicago → Cleveland (D). Chicago traded two seventh-round selections (209th and 225th overall) to Cleveland in exchange for three seventh-round selections (223rd, 232nd and 254th overall).
↑No. 212: Philadelphia → New England → San Francisco. Multiple trades: Philadelphia → New England (PD). Philadelphia traded a seventh-round selection (212th overall) to New England in exchange for WR Dietrich Jells. New England → San Francisco (D). New England traded a seventh-round selection (212th overall) to San Francisco in exchange for a 2001 sixth-round selection.
↑No. 213: Chicago → Tennessee (PD). Chicago traded a seventh-round selection (213th overall) to Tennessee in exchange for LB Lemanski Hall.
↑No. 216: Pittsburgh → Washington (PD). Pittsburgh traded a seventh-round selection (216th overall) to Washington in exchange for OT Shar Pourdanesh.
↑No. 225: Baltimore → St. Louis → Chicago. Multiple trades: Baltimore → St. Louis (PD). Baltimore traded a seventh-round selection (225th overall) and a 1999 fifth-round selection to St. Louis in exchange for QB Tony Banks. St. Louis → Chicago (D). See Round 4: Chicago → St. Louis. Chicago → Cleveland (D).No. 209: Chicago → Cleveland.
↑No. 229: Seattle → Green Bay (PD). Seattle traded a seventh-round selection (229th overall) to Green Bay in exchange for WR Derrick Mayes.
↑No. 230: Miami → San Francisco (PD). Miami traded a seventh-round selection (230th overall) to San Francisco in exchange for QB Jim Druckenmiller.
↑No. 231: Washington → Denver → Seattle → Oakland. Multiple trades: Washington → Denver (PD). Washington traded a seventh-round selection (231st overall) and a 2001 seventh-round selection to Denver in exchange for CB Tito Paul. Denver → Seattle (D). See Round 5: Seattle → Denver. Seattle → Oakland (D). Seattle traded a seventh-round selection (231st overall) to Oakland in exchange for a 2001 sixth-round selection.
↑No. 232: Minnesota → Cleveland → Chicago → Miami. Multiple trades: Minnesota → Cleveland (PD). Minnesota traded a seventh-round selection (232nd overall) and DT Stalin Colinet to Cleveland in exchange for DT Jerry Ball. Cleveland → Chicago (D). See Round 7: Chicago → Cleveland. Chicago → Miami (D). Chicago traded a seventh-round selection (232nd overall) and a 2001 seventh-round selection to Miami in exchange for P Brent Bartholomew.
↑No. 238: St. Louis → Oakland → Indianapolis. Multiple trades: St. Louis → Oakland (PD). St. Louis traded a seventh-round selection (238th overall) to Oakland in exchange for QB Paul Justin. Oakland → Indianapolis (D). Oakland traded a seventh-round selection (238th overall) to Indianapolis in exchange for a 2001 sixth-round selection.