2001 in Spain

February

• 5: Endesa and Iberdrola, two electrical companies announce that the merger process that began in October 2000 has stopped and will not be finalized.
• 11: 7 Technicians of the Compañía Lírica die in a traffic accident.
• 13: Javier Bardem is nominated for an Academy Award for his role in Julian Schnabel's film Before Night Falls, being the first Spanish actor to do so.
• 22: Terrorist group ETA execute a car bombing that kills two employees of the company Elektra in San Sebastián.

April

• 7: The Partido de Acción Socialista (PASOC) agrees to abandon its federal congress within the United and Alternative Left.
• 23: Madrid is chosen to be a World Book Capital

May

13: The EAJ-PNV/EA coalition (Basque Nationalist Party and Eusko Alkartasuna) attains a great victory during the Basque regional elections, forming a government for the next four years.

August

• 24: Singer Joaquin Sabina suffered a minor stroke because of excessive drug use that would lead him to the brink of death.
• 31: After the death of twelve patients undergoing hemodialysis in Valencia, Madrid and Barcelona, The Department of Pharmacy decides granting a protective detention of a dialyzer marketed by multinational Baxter.

December

• The Orquesta Ciudad de Almería, OCAL (City Orchestra of Almeria) is founded in the Province of Almería,