Standard benchmarks such as CUTEr and SBML curated models are used to test the performance of APOPT relative to solvers BPOPT, IPOPT, SNOPT, and MINOS. A combination of APOPT (Active Set SQP) and BPOPT (Interior Point Method) performed the best on 494 benchmark problems for solution speed and total fraction of problems solved.
↑WOpatent 2012005740,Lawson, K. W., Hedengren, J. D., Smith, L. C.,"Method for Controlling Bubble Formation in Polymerization Reactors",published 2012-01-12
↑Spivey, B. (2010). "Constrained Nonlinear Estimation for Industrial Process Fouling". Industrial & Engineering Chemistry Research. 49 (17): 7824–7831. doi:10.1021/ie9018116.