| Adolphus Frederick II | |
|---|---|
| Duke of Mecklenburg-Strelitz | |
| Duke of Mecklenburg-Strelitz | |
| Reign | 8 March 1701 – 12 May 1708 |
| Predecessor | Friedrich Wilhelm |
| Successor | Adolf Friedrich III |
| Born | 19 October 1658 Grabow |
| Died | 12 May 1708 (aged 49) |
| Spouse | |
| Issue Detail |
|
| House | Mecklenburg-Strelitz |
| Father | Adolf Frederick I |
| Mother | Maria Katharina of Brunswick-Dannenberg |
| Religion | Lutheranism |
Adolphus Frederick II (German: Adolf Friedrich II; 19 October 1658 – 12 May 1708), Duke of Mecklenburg, was the first Duke of the Mecklenburg-Strelitz, reigning from 1701 until his death. Mecklenburg-Strelitz was a part of the Holy Roman Empire.
He was born in Grabow as the posthumous son of Duke Adolf Frederick I of Mecklenburg and his second wife, Maria Katharina of Brunswick-Dannenberg (1616–1665).
In 1695, the Mecklenburg-Güstrow branch of the House of Mecklenburg became extinct and Adolphus Frederick's nephew, Frederick William, Duke of Mecklenburg-Schwerin, laid claim to the inheritance, a move which Adolphus Frederick opposed.
The dispute was settled in 1701 by dividing Mecklenburg-Güstrow between the two claimants. Frederick William took the Duchy of Mecklenburg-Schwerin, and Adolphus obtained the Principality of Ratzeburg and the Lordship of Stargard with the commanderies of Mirow and Nemerow, of which he formed the Duchy of Mecklenburg-Strelitz.
Following his death in 1708, Adolphus Frederick was succeeded as Duke by his son, Adolphus Frederick III.
In 1684, Adolphus Frederick II married firstly to Marie of Mecklenburg-Güstrow (19 July 1659 – 16 January 1701), daughter of Gustav Adolph, Duke of Mecklenburg-Güstrow. They had five children:
On 20 June 1702, Adolphus Frederick II married secondly to Princess Johanna of Saxe-Gotha (1 October 1680 – 9 July 1704), daughter of Frederick I, Duke of Saxe-Gotha-Altenburg, and Magdalena Sybille of Saxe-Weissenfels, who was his half-niece. There were no children from this marriage.

On 10 June 1705 at Neustrelitz, Adolphus Frederick II married thirdly to Princess Christiane Emilie of Schwarzburg-Sondershausen (13 March 1681 – 1 November 1751), daughter of Christian William I, Prince of Schwarzburg-Sondershausen, and Countess Antonie Sybille of Barby-Mühlingen (1641–1684). They had two children:
Through his granddaughter Charlotte, Adolphus Frederick is the ancestor of every British monarch beginning with George IV, who ascended the throne of the United Kingdom in 1820.