Amfenac

Amfenac
Clinical data
ATC code	none;
Identifiers
	IUPAC name (2-Amino-3-benzoylphenyl)acetic acid;
CAS Number	51579-82-9 ;
PubChem CID	2136;
IUPHAR/BPS	7565;
ChemSpider	2051 ;
UNII	28O5C1J38A;
KEGG	D07443 ;
ChEBI	CHEBI:75915 ;
ChEMBL	ChEMBL25146 ;
CompTox Dashboard (EPA)	DTXSID90199533 ;
Chemical and physical data
Formula	C15H13NO3
Molar mass	255.273 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(c1cccc(c1N)CC(=O)O)c2ccccc2;
	InChI InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18) ; Key:SOYCMDCMZDHQFP-UHFFFAOYSA-N ;
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Amfenac, also known as 2-amino-3-benzoylbenzeneacetic acid, is a nonsteroidal anti-inflammatory drug (NSAID) with acetic acid moiety.

References

↑ Hiranuma T, Kato S, Hachisu M (September 1988). "Analgesic action of amfenac Na, a non-steroidal anti-inflammatory agent". Journal of Pharmacobio-Dynamics. 11 (9): 612–9. doi:10.1248/bpb1978.11.612. PMID 3265150.

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[pmid3265150-1] Hiranuma T, Kato S, Hachisu M (September 1988). "Analgesic action of amfenac Na, a non-steroidal anti-inflammatory agent". Journal of Pharmacobio-Dynamics. 11 (9): 612–9. doi:10.1248/bpb1978.11.612. PMID 3265150.

v t e Nonsteroidal anti-inflammatory drugs (NSAIDs) (primarily M01A and M02A, also N02BA)
pyrazolones / pyrazolidines	Aminophenazone Ampyrone Azapropazone Clofezone Difenamizole Famprofazone Feprazone Kebuzone Metamizole Mofebutazone Morazone Nifenazone Oxyphenbutazone Phenazone Phenylbutazone Propyphenazone Sulfinpyrazone Suxibuzone^‡
salicylates	Aspirin (acetylsalicylic acid)^# Aloxiprin Benorylate Carbasalate calcium Diflunisal Dipyrocetyl Ethenzamide Guacetisal Magnesium salicylate Methyl salicylate Salsalate Salicin Salicylamide Salicylic acid (salicylate) Sodium salicylate
acetic acid derivatives and related substances	Aceclofenac Acemetacin Alclofenac Amfenac Bendazac Bromfenac Bufexamac Bumadizone Diclofenac Difenpiramide Etodolac Felbinac Fenclozic acid Fentiazac Indometacin Indometacin farnesil Isoxepac Ketorolac Lonazolac Mofezolac Oxametacin Prodolic acid Proglumetacin Sulindac Tiopinac Tolmetin Zomepirac^†
oxicams	Ampiroxicam Droxicam Isoxicam Lornoxicam Meloxicam Piroxicam Pivoxicam Tenoxicam
propionic acid derivatives (profens)	Alminoprofen Benoxaprofen^† Carprofen^‡ Dexibuprofen Dexketoprofen Fenbufen Fenoprofen Flunoxaprofen Flurbiprofen Ibuprofen^# Ibuproxam Indoprofen^† Ketoprofen Loxoprofen Miroprofen Naproxen Oxaprozin Pelubiprofen Piketoprofen Pirprofen Suprofen Tarenflurbil Tepoxalin^‡ Tiaprofenic acid Vedaprofen^‡ Zaltoprofen COX-inhibiting nitric oxide donator: Naproxcinod
n-arylanthranilic acids (fenamates)	Azapropazone Clonixin Etofenamate Floctafenine Flufenamic acid Flunixin Flutiazin Glafenine^† Meclofenamic acid Mefenamic acid Morniflumate Niflumic acid Tolfenamic acid
COX-2 inhibitors (coxibs)	Apricoxib Celecoxib (+tramadol) Cimicoxib^‡ Deracoxib^‡ Etoricoxib Firocoxib^‡ Lumiracoxib^† Mavacoxib^‡ Parecoxib Robenacoxib^‡ Rofecoxib^† Valdecoxib^†
other	Aminopropionitrile Benzydamine Chondroitin sulfate Diacerein Fluproquazone Glucosamine Glycosaminoglycan Grapiprant^‡ Hyperforin Nabumetone Nimesulide Oxaceprol Proquazone Superoxide dismutase / orgotein Tenidap
NSAID combinations	Ibuprofen/famotidine Ibuprofen/hydrocodone Ibuprofen/oxycodone Ibuprofen/paracetamol Meloxicam/bupivacaine Meloxicam/rizatriptan Naproxen/diphenhydramine Naproxen/esomeprazole Naproxen/paracetamol
Key: underline indicates initially developed first-in-class compound of specific group; ^#WHO-Essential Medicines; ^†withdrawn drugs; ^‡veterinary use.
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Clinical data

ATC code	none
Identifiers
IUPAC name (2-Amino-3-benzoylphenyl)acetic acid
CAS Number	51579-82-9^Y
PubChem CID	2136
IUPHAR/BPS	7565
ChemSpider	2051^Y
UNII	28O5C1J38A
KEGG	D07443^Y
ChEBI	CHEBI:75915^N
ChEMBL	ChEMBL25146^Y
CompTox Dashboard (EPA)	DTXSID90199533
Chemical and physical data
Formula	C₁₅H₁₃NO₃
Molar mass	255.273 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C(c1cccc(c1N)CC(=O)O)c2ccccc2
InChI InChI=1S/C15H13NO3/c16-14-11(9-13(17)18)7-4-8-12(14)15(19)10-5-2-1-3-6-10/h1-8H,9,16H2,(H,17,18)^Y Key:SOYCMDCMZDHQFP-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)

Amfenac

See also

References