Picotamide

Picotamide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 4-methoxy-N,N'-bis(pyridin-3-ylmethyl)isophthalamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.046.572 Edit this at Wikidata
Chemical and physical data
FormulaC21H20N4O3
Molar mass376.416 g·mol−1
3D model (JSmol)
  • O=C(NCc1cccnc1)c3cc(C(=O)NCc2cccnc2)c(OC)cc3
  • InChI=1S/C21H20N4O3/c1-28-19-7-6-17(20(26)24-13-15-4-2-8-22-11-15)10-18(19)21(27)25-14-16-5-3-9-23-12-16/h2-12H,13-14H2,1H3,(H,24,26)(H,25,27) checkY
  • Key:KYWCWBXGRWWINE-UHFFFAOYSA-N checkY
  (verify)

Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor. Picotamide is licensed in Italy for the treatment of clinical arterial thrombosis and peripheral artery disease.