| Aptychodon Temporal range: Late Cretaceous, | |
|---|---|
| Teeth from the holotype of A. cretaceus | |
| Scientific classification | |
| Kingdom: | Animalia |
| Phylum: | Chordata |
| Class: | Reptilia |
| Superorder: | †Sauropterygia |
| Order: | †Plesiosauria |
| Genus: | †Aptychodon von Reuss, 1855 |
| Type species | |
| †Aptychodon cretaceus von Reuss, 1855 | |
Aptychodon (meaning "unwrinkled tooth") is an extinct genus of plesiosaur from the Late Cretaceous of the Czech Republic. The type species is A. cretaceus.

The holotype consists of incompletely preserved teeth and they were discovered at White Mountain near Prague, Czech Republic. They were then sent to the Prague Museum before von Reuss (1855) described the teeth and created the species Aptychodon cretaceius.
The teeth of Aptychodon are conical and curved towards one side despite mostly being straight. They also measure between 2.5 centimetres (0.98 in) and 13 centimetres (5.1 in) in length.
Aptychodon has been classified as a potential synonym of Polyptychodon interruptus by later authors. Most authors classify Aptychodon within a basal position in Plesiosauria.