Clomegestone

Clomegestone
Identifiers
  • (1S,2R,10R,11S,13R,14R,15S)-14-Acetyl-8-chloro-14-hydroxy-2,13,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-6,8-dien-5-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H29ClO3
Molar mass376.92 g·mol−1
3D model (JSmol)
  • CC1CC2C3C=C(C4=CC(=O)CCC4(C3CCC2(C1(C(=O)C)O)C)C)Cl
  • InChI=1S/C22H29ClO3/c1-12-9-17-15-11-19(23)18-10-14(25)5-7-20(18,3)16(15)6-8-21(17,4)22(12,26)13(2)24/h10-12,15-17,26H,5-9H2,1-4H3/t12-,15-,16+,17+,20-,21+,22+/m1/s1
  • Key:GQBSINXSPAZDSK-ROXMKHFISA-N

Clomegestone (INN; also known as clomagestone or 6-chloro-17α-hydroxy-16α-methylpregna-4,6-diene-3,20-dione) is a steroidal progestin of the 17α-hydroxyprogesterone group that was never marketed. An acetate ester, clomegestone acetate, also exists, and similarly was never marketed.

References

  1. 1 2 Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 297–. ISBN 978-1-4757-2085-3.
  2. ↑ World Health Organization (2013), The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances (PDF), p. 65, archived from the original (PDF) on August 8, 2016