As a true freshman at Utah in 2021, Bishop played in 10 games and started the final six. He finished the year with 54 tackles and three sacks. As a sophomore in 2022, he started 13 of 14 games and led the team with 83 tackles and had one interception and 1.5 sacks. He returned to Utah for his junior year in 2023.
Bishop (#24) warming up with the Bills before a game against the Tampa Bay Buccaneers in 2025
Bishop was selected by the Buffalo Bills with the 60th overall pick in the second round of the 2024 NFL draft. He spent the majority of his rookie season as a backup to Damar Hamlin, but started on occasion. Bishop later won the starting safety spot in his sophomore season, playing alongside Taylor Rapp until the latter's season-ending injury. He caught his first career interception against the New Orleans Saints, foiling the Saints' attempt at executing their own version of the Philly Special. Bishop played a major role in the Bills' win over the Kansas City Chiefs in Week 9, leading the team in tackles and forcing a turnover on downs.
Bishop's play improved noticeably throughout his second season, with Sports Illustrated attributing it to mentorship from veteran teammate Jordan Poyer. Joe Buscaglia of The Athletic, who analyzed Bishop's play, wrote that Bishop became more confident and aware later in the season, taking advantage of his athleticism to make plays after struggling with positioning himself earlier on. Bishop totaled 85 tackles (53 solo), three interceptions, seven passes defensed, and two sacks in his sophomore season. In the playoffs, he made a crucial interception of Trevor Lawrence during the Bills' Wild Card game against the Jacksonville Jaguars, sealing Buffalo's first road playoff win since 1992.
On June 18, 2026, it was announced that Bishop had undergone surgery on his left knee, but would be expected to return in training camp.
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