Drew was probably named after Robert Drew, a local resident. Drew post office was established in 1902 and discontinued in 1971. In 1915 the community had a public school, and the nearest railroad point was 32 miles away in Riddle. As of 1990 there were only a few houses. Drew has a general store and a museum in the former Tison School building, built of logs in 1906.
At one time Drew's economy was based primarily on logging, but in a 2006 study, the federal government identified the Milo-Tiller-Drew area as a "community of concern" because of the negative impact the Northwest Forest Plan had on it.