ESCAPPM or ESCHAAPPM is a mnemonic for a group of gram-negative bacteria with inducible beta-lactamase activity that is chromosomally mediated.
In vitro sensitivities are not applicable in vivo.
In general, treatment with cephalosporins results in induction of AmpC beta-lactamase. Treatment with an aminoglycoside or carbapenem is usually indicated. Carbapenems are a class of beta-lactam antibiotics with a broad spectrum of antibacterial activity. They have a structure that renders them highly resistant to beta-lactamases. Examples of carbapenems include meropenem and imipenem.