Hyaluronoglucuronidase

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Hyaluronoglucuronidase
Hyaluronoglucuronidase
Identifiers
EC no.	3.2.1.36
CAS no.	37288-34-9
Databases
BRENDA	enzyme data
ExPASy	NiceZyme view
KEGG	enzyme entry
MetaCyc	metabolic pathway
Rhea	reactions
PDB structures	RCSB PDB PDBe PDBsum
PMC
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PMC	articles
PubMed	articles
NCBI	proteins

Hyaluronoglucuronidase (EC 3.2.1.36, hyaluronidase, glucuronoglucosaminoglycan hyaluronate lyase, orgelase) is an enzyme with systematic name hyaluronate 3-glycanohydrolase. This enzyme catalyses the following chemical reaction

Random hydrolysis of (1→3)-linkages between β-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate

References

↑ Linker A, Meyer K, Hoffman P (April 1960). "The production of hyaluronate oligosaccharides by leech hyaluronidase and alkali". The Journal of Biological Chemistry. 235 (4): 924–7. doi:10.1016/S0021-9258(18)69452-9. PMID 14417285.
↑ Meyer K, Hoffman P, Linker A (1960). "Hyaluronidases". In Boyer PD, Lardy H, Myrbaumlck K (eds.). The Enzymes. Vol. 4 (2nd ed.). New York: Academic Press. pp. 447–460.

External links

Hyaluronoglucuronidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[1] Linker A, Meyer K, Hoffman P (April 1960). "The production of hyaluronate oligosaccharides by leech hyaluronidase and alkali". The Journal of Biological Chemistry. 235 (4): 924–7. doi:10.1016/S0021-9258(18)69452-9. PMID 14417285.

[2] Meyer K, Hoffman P, Linker A (1960). "Hyaluronidases". In Boyer PD, Lardy H, Myrbaumlck K (eds.). The Enzymes. Vol. 4 (2nd ed.). New York: Academic Press. pp. 447–460.

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)