As a freshman in 2021-22, Reese averaged 5.7 points and 4.4 rebounds in 17.7 minutes per game. Ahead of the 2022-23 season, he became a full-time starter for the Terrapins. On February 16, 2023, Reese helped the Terrapins to an upset win over #3 Purdue. He finished the 2022-23 season averaging 11.4 points, 7.2 rebounds and 1.2 blocks per game, earning All-Big Ten honorable mention.
In 2023-24, Reese averaged 13.7 points, 9.5 rebounds and 1.9 blocks per game and earned all-Big Ten honorable mention. On November 11, 2024, he put up 21 points and nine rebounds in a victory over Florida A&M. On January 23, 2025, Reese put up 27 points, 17 rebounds, and three blocks in a blowout win over Illinois. On January 29, he put up 14 points and eight rebounds in a victory over Wisconsin. On March 5, Reese tallied six points and four rebounds in a win over Michigan.
On February 28, 2026, Reese was signed to a two-way contract by the Washington Wizards. His first game with the team came two days later, against the Houston Rockets, where he was pressed into service as the Wizards' starting center as all the team's other big men were out with injury. Reese went 1-for-3 in shooting on the night, earning his first two points as an NBA player, in addition to four rebounds and three steals. Reese also committed three turnovers and fouled out after almost 28 minutes that same night. On March 5, Reese put up a double-double with 18 points and 20 rebounds, 10 offensive and 10 defensive, in a 122–112 loss to the Utah Jazz. He became the first player since Antawn Jamison in 2010 to put up 10 offensive and 10 defensive rebounds in a game in Wizards franchise history. On March 25, Reese had another double-double with 26 points, 17 rebounds, a steal, and a block across 30 minutes of a 133-110 win over the Jazz.
On August 20, 2026, Reese was traded to the Denver Nuggets. However, he was released by the Nuggets on August 28.
Personal life
Reese is the brother of WNBA All-Star Angel Reese. Reese's mother played college basketball for UMBC, where she was inducted into the Athletics Hall of Fame and her number 10 jersey was retired. She later played professionally in Luxembourg, Reese's father, Michael Reese, played basketball for Boston College and Loyola (Maryland) before embarking on a professional career in Luxembourg, Cyprus, Austria, and Portugal.
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