La Reina | |
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View from the Mall Plaza Egaña to the east | |
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| Coordinates: 33°27′S 70°33′W / 33.450°S 70.550°W | |
| Country | Chile |
| Region | Santiago Metropolitan |
| Province | Santiago |
| Government | |
| • Type | Municipality |
| • Mayor | José Manuel Palacios (UDI) |
| Area | |
• Total | 23.4 km2 (9.0 sq mi) |
| Population (2002 Census) | |
• Total | 96,762 |
| • Density | 4,140/km2 (10,700/sq mi) |
| • Urban | 96,762 |
| • Rural | 0 |
| Sex | |
| • Men | 44,293 |
| • Women | 52,469 |
| Time zone | UTC-4 (CLT) |
| Area code | 56 + |
| Website | Municipality of La Reina |



La Reina (Spanish for "The Queen"; distorted from Larraín) is a commune of Chile located in Santiago Province, Santiago Metropolitan Region, created in 1963 from an eastern portion of the Ñuñoa commune. It belongs to the Northeastern zone of Santiago de Chile.
La Reina is a residential commune inhabited by mostly mid- to upper-mid income families and high-income groups. The Eulogio Sánchez Airport and Military Hospital are both located in the southern part of the commune.
According to the 1999 census of the National Statistics Institute, La Reina spans an area of 23.4 km2 (9 sq mi) and has 96,762 inhabitants (44,293 men and 52,469 women), and the commune is an entirely urban area. The population grew by 4.7% (4,352 persons) between the 1990 and 1999 censuses. The 2003 projected population was 96,551.[failed verification]
As a commune, La Reina is a third-level administrative division of Chile administered by a municipal council, headed by a mayor who is directly elected every four years. The mayor since 2016 has been José Manuel Palacios Parra (UDI). The municipal council for the 2024–2028 term has the following members:
La Reina belongs to Chile's Electoral District No. 11, along with the communes of Lo Barnechea, Vitacura, Las Condes, and Peñalolén, and to the VII Senatorial Constituency (Metropolitan Region of Santiago).
In the Chamber of Deputies of Chile, it is represented (2022-2026 term) by:
In the Senate of Chile, it was represented by Carlos Montes from the PS and Manuel José Ossandón from RN during the 2014-2022 period.