Megasphaera
| Megasphaera | |
|---|---|
Scientific classification  | |
| Domain: | Bacteria |
| Kingdom: | Bacillati |
| Phylum: | Bacillota |
| Class: | Negativicutes |
| Order: | Veillonellales |
| Family: | Veillonellaceae |
| Genus: | Megasphaera Rogosa 1971 |
| Type species | |
| Megasphaera elsdenii (Gutierrez et al. 1959) Rogosa 1971 | |
| Species | |
Megasphaera is a genus of Bacillota bacteria classified within the class Negativicutes. Several species in the genus, including M. elsdenii and M. hexanoica, are known to utilize lactate.
This classification has been reexamined. This genus appears to be a member of the Clostridia.
Phylogeny
The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature (LPSN) and National Center for Biotechnology Information (NCBI).
| 16S rRNA based LTP_10_2024 | 120 marker proteins based GTDB 10-RS226 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Unassigned species:
- M. jansseni Heng et al. 2025
- "M. vaginalis" Srinivasan et al. 2021 non Bordigoni et al. 2020
See also
References
- 1 2 3 Megasphaera in LPSN; Freese, H. M.; Meier-Kolthoff, J. P.; Sardà Carbasse, J.; Afolayan, A. O.; Göker, M. (2026). "TYGS and LPSN in 2025: a Global Core Biodata Resource for genome-based classification and nomenclature of prokaryotes within DSMZ Digital Diversity". Nucleic Acids Research. 54 (D1): D884–D891. doi:10.1093/nar/gkaf1110.
- 1 2 Schoch CL; et al. "Megasphaera". National Center for Biotechnology Information (NCBI) taxonomy database. Retrieved 2025-06-05.
- ↑ Strachan, CR.; et al. (2025). "Distinct lactate utilization strategies drive niche differentiation between two co-existing Megasphaera species in the rumen microbiome". The ISME Journal. 19 (1) wraf147. doi:10.1093/ismejo/wraf147. PMC 12342382.
- ↑ Yutin N, Galperin MY (2013) A genomic update on Clostridial phylogeny: Gram-negative spore formers and other misplaced Clostridia. Environ Microbiol doi: 10.1111/1462-2920.12173
- ↑ "The LTP". Retrieved 10 December 2024.
- ↑ "LTP_all tree in newick format". Retrieved 10 December 2024.
- ↑ "LTP_10_2024 Release Notes" (PDF). Retrieved 10 December 2024.
- ↑ "GTDB release 10-RS226". Genome Taxonomy Database. Retrieved 1 May 2025.
- ↑ "bac120_r226.sp_label". Genome Taxonomy Database. Retrieved 1 May 2025.
- ↑ "Taxon History". Genome Taxonomy Database. Retrieved 1 May 2025.
- Arik, H. D., Gulsen, N., Hayirli, A., & Alatas, M. S. (2019). Efficacy of Megasphaera elsdenii inoculation in subacute ruminal acidosis in cattle. Journal of animal physiology and animal nutrition, 103(2), 416–426.
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