PXK

PXK
Identifiers
Aliases	PXK, MONaKA, PX domain containing serine/threonine kinase like
External IDs	OMIM: 611450; MGI: 1289230; GeneCards: PXK
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14 A1|14 4.7 cM Start 14,304,656 bp End 14,371,562 bp
Gene ontology Molecular function nucleotide binding actin binding protein kinase activity phosphatidylinositol binding ATP binding protein C-terminus binding Cellular component cytoplasm membrane nucleus microtubule organizing center cytosol plasma membrane protein-containing complex Biological process protein phosphorylation inflammatory response negative regulation of ATP-dependent activity negative regulation of ion transport modulation of chemical synaptic transmission regulation of membrane potential Sources:Amigo / QuickGO
Orthologs Databases NCBI: entry; OMA: entry Species Human Mouse Entrez 54899 218699 Ensembl ENSG00000168297 ENSMUSG00000033885 UniProt Q7Z7A4 Q8BX57 RefSeq (mRNA) NM_001289095 NM_001289096 NM_001289098 NM_001289099 NM_001289100 NM_001289101 NM_017771 NM_145458 NM_178279 NM_001360313 NM_001360314 NM_001360315 NM_001360316 RefSeq (protein) NP_001276024 NP_001276025 NP_001276027 NP_001276028 NP_001276029 NP_001276030 NP_060241 NP_001336417 NP_001336418 NP_001336419 NP_001336420 NP_001336421 NP_001336422 NP_001336423 NP_001336424 NP_001336425 NP_001336426 NP_001336427 NP_001336428 NP_001336429 NP_001336430 NP_001336431 NP_001336432 NP_001336433 NP_001336435 NP_001336436 NP_001336437 NP_001336438 NP_001336439 NP_001336440 NP_001336441 NP_001336442 NP_001336443 NP_001336444 NP_001336445 NP_001336446 NP_001336447 NP_001336448 NP_001336449 NP_001336450 NP_001336451 NP_001336453 NP_001336454 NP_001336455 NP_001336456 NP_001336457 NP_001336458 NP_001336459 NP_001336460 NP_001336461 NP_001336462 NP_001336463 NP_001336464 NP_001336465 NP_001336466 NP_001336467 NP_001336468 NP_001336469 NP_663433 NP_840063 NP_001347242 NP_001347243 NP_001347244 NP_001347245 Location (UCSC) n/a Chr 14: 14.3 – 14.37 Mb PubMed search
Wikidata
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PX domain containing serine/threonine kinase also known as PXK is a protein which in humans is encoded by the PXK gene.

Function

PXK binds to the Na⁺/K⁺-ATPase beta-1 (ATP1B1) and beta-3 (ATP1B3) subunits and modulates both Na⁺/K⁺-ATPase enzymatic and ion pump activities.

See also

• PX domain

References

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by adding missing information.

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