Pre-colonial period
- 1365 – The Majapahit manuscript Nagarakretagama mentions Makassar as a part of Majapahit's conquered territories, as one of the first written mentions of Makassar.
- Late 15th century – The port of Bandar Tallo developed at the mouth of the Tallo River, within present-day Makassar.
- c. 1513 – Portuguese traveler Tomé Pires mentions Makassar in his Suma Oriental, though he described the whole island of Sulawesi as "Makassar".
- 1544 – A Portuguese delegation was dispatched from Portuguese Malacca to open trade (mainly in sandalwood) with Makassar.
- 1545 – A stone and clay fort, Fort Ujungpandang, was constructed by the Sultan of Gowa in modern Makassar.
- c. 1605 – The Dutch established a permanent trading presence in Makassar.
- 9 November 1607 – Monarchs of Gowa and Tallo adopted Islam and announced the Islamisation of their subjects. Celebrated today as Makassar's founding date.
- 1613 – An English factory was established in Makassar by John Jourdain of the English East India Company.
- 1615:
- Trade between Makassar and Spanish Manila commenced.
- Makassar's population was estimated to reach 25,000.
- 1618 – The Danish East India Company established a factory in Makassar.
- 1619 – Chinese merchants began to operate in Makassar.
- 1622 – French traders establish their presence in Makassar.
- 1634–1635 – Fort Ujungpandang was further expanded and fortified.
- 1636 – Makassar was struck by a "plague" epidemic, which reportedly killed 60 thousand people within 40 days.
- 1641 – Following the Dutch conquest of Portuguese Malacca, a large number of Portuguese inhabitants of the city relocated to Makassar. By the mid-century, the city was recorded to have around three thousand Catholics, mostly Portuguese.
- 1650s – A permanent agent of the Golconda Sultanate operated in the city.
- 1666–1669 – The Makassar War:
- 18 November 1667 – Fort Ujungpandang was ceded to the Dutch under the Treaty of Bongaya, and renamed Fort Rotterdam. The treaty also stipulated for the removal of the English factory from the city.
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